| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Collagen IV / COL4A3 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
Western blot: 1:500-1000 |
| Intented use: |
This COL4A3 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
1285 |
| Uniprot #: |
Q01955 |
| Purity: |
Antigen affinity |
| Description: |
forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen, Type IV collagen is the major structural component of glomerular basement membranes (GBM) |
| Immunogen: |
A portion of amino acids 141-173 from the human protein was used as the immunogen for the COL4A3 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the COL4A3 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Collagen IV / COL4A3 |
| Short name: |
Collagen IV Antibody / COL4A3 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
a 3 ( this GO odpasture antigen), classification IV, Collagen IV (Antibody to) / collagen |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
COL4A3 and IDBG-644230 and ENSBTAG00000021316 and 317711, COL4A3 and IDBG-82471 and ENSG00000169031 and 1285, Col4a3 and IDBG-253830 and ENSMUSG00000079465 and 12828, Extracellular, alpha 3 ( this GO odpasture antigen), metalloendopeptidase inhibitor activity, this GO :0005178 and integrin binding and molecular function this GO :0005198 and structural molecule activity and molecular function this GO :0005201 and extracellular matrix structural constituent and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005581 and collagen trimer and cellular component this GO :0005587 and collagen type IV trimer and cellular component this GO :0005604 and basement membrane and cellular component this GO :0005788 and endoplasmic reticulum lumen and cellular component this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0007155 and cell adhesion and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007411 and axon guidance and biological process this GO :0007605 and sensory perception of sound and biological process this GO :0008015 and blood circulation and biological process this GO :0008191 and metalloendopeptidase inhibitor activity and molecular function this GO :0008283 and cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009749 and response to glucose and biological process this GO :0010951 and negative regulation of endopeptidase activity and biological process this GO :0016525 and negative regulation of angiogenesis and biological process this GO :0022617 and extracellular matrix disassembly and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030574 and collagen catabolic process and biological process this GO :0032836 and glomerular basement membrane development and biological process this GO :0072577 and endothelial cell apoptotic process and biological process, this GO :0005178 : integrin binding, this GO :0005178 : integrin binding and also this GO :0005198 : structural molecule activity and also this GO :0005201 : extracellular matrix structural constituent and also this GO :0005515 : protein binding and also this GO :0008191 : metalloendopeptidase inhibitor activity, this GO :0005198 : structural molecule activity, this GO :0005201 : extracellular matrix structural constituent, this GO :0005515 : protein binding, this GO :0008191 : metalloendopeptidase inhibitor activity, type IV, collagen |
| Identity: |
2204 |
| Gene: |
COL4A3 |
More about : COL4A3 |
| Long gene name: |
collagen type IV alpha 3 chain |
| Synonyms gene name: |
alpha 3 (Goodpasture antigen) , collagen, type IV |
| Synonyms name: |
tumstatin |
| Locus: |
2q36, 3 |
| Discovery year: |
1991-09-12 |
| Entrez gene record: |
1285 |
| Pubmed identfication: |
1737849 |
| RefSeq identity: |
NM_000091 |
| Classification: |
Collagens |
| Havana BLAST/BLAT: |
OTTHUMG00000149891 |
| Locus Specific Databases: |
LRG_230 |