| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Integrin alpha 3 (ITGA3) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:2000-4000 |
| Notes: |
Titration of the Integrin alpha 3 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This Integrin alpha 3 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P26006 |
| Purity: |
Antigen affinity |
| Description: |
Alpha- 3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration, Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, collagen, epiligrin, formation of invadopodia and matrix degradation processes, laminin, promoting cell invasion, thrombospondin and CSPG4, Integrin alpha-3/beta-1 is a receptor for fibronectin |
| Immunogen: |
This Integrin alpha 3 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 165-199 amino acids from the N-terminal region of human ITGA3 |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Integrin alpha 3 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Integrin alpha 3 (ITGA3) |
| Short name: |
Integrin alpha 3 Antibody (ITGA3) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
a 3 (antigen CD49C, a 3 subunit on VLA-3 receptor)), Integrin a 3 (Antibody to) (integrin |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD49C and GAP-B3 and GAPB3 and ILNEB and MSK18 and VCA-2 and VL3A and VLA3a, Cell surfaces, ITGA3 and IDBG-58012 and ENSG00000005884 and 102725477, ITGA3 and IDBG-638685 and ENSBTAG00000019498 and 508490, Itga3 and IDBG-209447 and ENSMUSG00000001507 and 16400, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor), protein heterodimerization activity, this GO :0001764 and neuron migration and biological process this GO :0001968 and fibronectin binding and molecular function this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005518 and collagen binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007160 and cell-matrix adhesion and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007507 and heart development and biological process this GO :0007596 and blood coagulation and biological process this GO :0007613 and memory and biological process this GO :0008305 and integrin complex and cellular component this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0010628 and positive regulation of gene expression and biological process this GO :0010634 and positive regulation of epithelial cell migration and biological process this GO :0010811 and positive regulation of cell-substrate adhesion and biological process this GO :0010976 and positive regulation of neuron projection development and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016323 and basolateral plasma membrane and cellular component this GO :0019904 and protein domain specific binding and molecular function this GO :0030198 and extracellular matrix organization and biological process this GO :0030426 and growth cone and cellular component this GO :0031345 and negative regulation of cell projection organization and biological process this GO :0034667 and integrin alpha3-beta1 complex and cellular component this GO :0034698 and response to this GO nadotropin and biological process this GO :0042493 and response to drug and biological process this GO :0043235 and receptor complex and cellular component this GO :0043236 and laminin binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045202 and synapse and cellular component this GO :0046872 and metal ion binding and molecular function this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050900 and leukocyte migration and biological process this GO :0060135 and maternal process involved in female pregnancy and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0001968 : fibronectin binding, this GO :0001968 : fibronectin binding and also this GO :0005178 : integrin binding and also this GO :0005515 : protein binding and also this GO :0005518 : collagen binding and also this GO :0019904 : protein domain specific binding and also this GO :0043236 : laminin binding and also this GO :0046872 : metal ion binding and also this GO :0046982 : protein heterodimerization activity, this GO :0005178 : integrin binding, this GO :0005515 : protein binding, this GO :0005518 : collagen binding, this GO :0019904 : protein domain specific binding, this GO :0043236 : laminin binding, this GO :0046872 : metal ion binding, this GO :0046982 : protein heterodimerization activity, 3675, integrin |
| Identity: |
6139 |
| Gene: |
ITGA3 |
More about : ITGA3 |
| Long gene name: |
integrin subunit alpha 3 |
| Synonyms gene: |
MSK18 |
| Synonyms gene name: |
alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) , antigen identified by monoclonal antibody J143 integrin |
| Synonyms: |
CD49c VLA3a VCA-2 GAP-B3 |
| Synonyms name: |
alpha 3 subunit of VLA-3 receptor antigen CD49C |
| Locus: |
17q21, 33 |
| Discovery year: |
1992-02-27 |
| GenBank acession: |
M59911 |
| Entrez gene record: |
3675 |
| Pubmed identfication: |
1655803 9704023 |
| RefSeq identity: |
NM_005501 |
| Classification: |
Integrin alpha subunits CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000161890 |