Egfr Antibody

Catalog number:	F52880-0.4ML Buy Now
Price:	348 €
Supplier:	MBS Polyclonals
Product name:	Egfr Antibody
Quantity:	0.12 ml
Other quantities:	0.08 ml 199€ 0.1mg 406€ 0.1ml 263€ 0.4 ml 406€ 1 mililiter Concentrate 912€ 1 vial 591€ 1 x 1 vial 486€ 100ug 630€ 100ul 370€ 100ul Concentrate 288€ 15 ml 763€ 200ug 536€ 3 ml 310€ 5 + Control Slides 304€ 500ul Concentrate 641€ 7 ml 464€
Related search:	egfr receptor antibodies gene long alternative

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Category:	Antibody
Concentration:	pH 7, with 0, 09% sodium azide, 4, In 1X PBS
Form:	Antigen affinity purified
Conjugation:	Unconjugated
Clone:	Polyclonal antibody
Recognised antigen:	Egfr
Host animal:	Rabbit (Oryctolagus cuniculus)
Clonality:	Polyclonal (rabbit origin)
Species reactivity:	Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus)
Tested applications:	ELISA, WB
Recommended dilutions:	Western blot: 1:1000
Notes:	Titration of the Egfr antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented use:	This Egfr antibodyis to be used only for research purposes and not for diagnostics
Uniprot #:	Q01279
Purity:	Antigen affinity
Description:	Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, Also directly phosphorylates other proteins like RGS16, Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin, BTC/betacellulin, Known ligands include EGF, Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues, May also activate the NF-kappa-B signaling cascade, PI3 kinase-AKT, PLCgamma-PKC and STATs modules, TGFA/TGF-alpha, The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling, amphiregulin, epigen/EPGN, epiregulin/EREG and HBEGF/heparin-binding EGF, Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses
Immunogen:	This mouse Egfr antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 1116-1130 amino acids from the human region of mouse Egfr
Storage:	Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Egfr antibody and store frozen at -20 deg
Properties:	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target:	Egfr
Short name:	Egfr Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Alternative name:	epidermal growth factor receptor (Antibody to)
Alternative technique:	antibodies
Identity:	40207
Gene:	EGFR-AS1 | More about : EGFR-AS1
Long gene name:	EGFR antisense RNA 1
Locus:	7p11, 2
Discovery year:	2012-11-06
Entrez gene record:	100507500
Pubmed identfication:	26271667
RefSeq identity:	NR_047551
Classification:	Long non-coding RNAs
Havana BLAST/BLAT:	OTTHUMG00000156126

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