| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
PHB |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the PHB antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This PHB antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P35232 |
| Purity: |
Antigen affinity |
| Description: |
As yet it is unclear if the protein or the mRNA exhibits this effect, It has a role in regulating proliferation, May play a role in regulating mitochondrial respiration activity and in aging, Prohibitin inhibits DNA synthesis |
| Immunogen: |
This PHB antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 73-107 amino acids from the N-terminal region of human PHB |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the PHB antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
PHB |
| Short name: |
PHB Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
prohibitin (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0007165 and signal transduction and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0010944 and negative regulation of transcription by competitive promoter binding and biological process this GO :0016020 and membrane and cellular component this GO :0016575 and histone deacetylation and biological process this GO :0019899 and enzyme binding and molecular function this GO :0030308 and negative regulation of cell growth and biological process this GO :0042826 and histone deacetylase binding and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0050847 and progesterone receptor signaling pathway and biological process this GO :0060766 and negative regulation of androgen receptor signaling pathway and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071354 and cellular response to interleukin-6 and biological process this GO :0071897 and DNA biosynthetic process and biological process this GO :2000323 and negative regulation of glucocorticoid receptor signaling pathway and biological process, HEL-215 and HEL-S-54e and PHB1, PHB and IDBG-57598 and ENSG00000167085 and 5245, PHB and IDBG-638810 and ENSBTAG00000017120 and 530409, Phb and IDBG-209638 and ENSMUSG00000038845 and 18673, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000981 and sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0001649 and osteoblast differentiation and biological process this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005743 and mitochondrial inner membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006260 and DNA replication and biological process this GO :0006355 and regulation of transcription, this GO :0000981 : sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0000981 : sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0005515 : protein binding and also this GO :0019899 : enzyme binding and also this GO :0042826 : histone deacetylase binding and also this GO :0044212 : transcription regulatory region DNA binding, this GO :0005515 : protein binding, this GO :0019899 : enzyme binding, this GO :0042826 : histone deacetylase binding, this GO :0044212 : transcription regulatory region DNA binding, transcription regulatory region DNA binding, 237880, prohibitin |
| Identity: |
8912 |
| Gene: |
PHB |
More about : PHB |
| Long gene name: |
prohibitin |
| Synonyms: |
PHB1 |
| Locus: |
17q21, 33 |
| Discovery year: |
1991-03-04 |
| Entrez gene record: |
5245 |
| Pubmed identfication: |
10376528 8244394 |
| RefSeq identity: |
NM_002634 |
| Havana BLAST/BLAT: |
OTTHUMG00000134271 |