| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CFP |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, FACS, WB |
| Recommended dilutions: |
Flow Cytometry: 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the CFP antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This CFP antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P27918 |
| Purity: |
Antigen affinity |
| Description: |
Mutations in this gene result in two forms of properdin deficiency, This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell, which results in high susceptibility to meningococcal infections, This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system |
| Immunogen: |
A portion of amino acids 197-223 from the human protein was used as the immunogen for this CFP antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CFP antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CFP |
| Short name: |
CFP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
complement factor properdin (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BFD and PFC and PFD and PROPERDIN, CFP and IDBG-61793 and ENSG00000126759 and 5199, CFP and IDBG-636742 and ENSBTAG00000015815 and 539605, Cfp and IDBG-135734 and ENSMUSG00000001128 and 18636, Extracellular, alternative pathway and biological process this GO :0030449 and regulation of complement activation and biological process this GO :0031012 and extracellular matrix and cellular component this GO :0042742 and defense response to bacterium and biological process this GO :0045087 and innate immune response and biological process, this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006955 and immune response and biological process this GO :0006956 and complement activation and biological process this GO :0006957 and complement activation, complement factor properdin |
| Identity: |
8864 |
| Gene: |
CFP |
More about : CFP |
| Long gene name: |
complement factor properdin |
| Synonyms gene: |
PFC |
| Synonyms gene name: |
complement , properdin P factor |
| Locus: |
Xp11, 23 |
| Discovery year: |
1989-06-07 |
| GenBank acession: |
M83652 |
| Entrez gene record: |
5199 |
| Pubmed identfication: |
1783405 |
| RefSeq identity: |
NM_002621 |
| Classification: |
Complement system |
| Havana BLAST/BLAT: |
OTTHUMG00000021451 |
| Locus Specific Databases: |
PFCbase: Mutation registry for properdin deficiency Mental Retardation database LRG_129 |