| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
STING (TMEM173) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, FACS, IHC, WB |
| Recommended dilutions: |
Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes: |
Titration of the STING antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This STING antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q86WV6 |
| Purity: |
Antigen affinity |
| Description: |
able to activate both NFkB and IRF3 transcription pathways to induce expression of type I interferon (IFN-a and IFN-b) and exert a potent anti-viral state following expression, Stimulator of interferon genes (STING) acts as a facilitator of innate immune signaling |
| Immunogen: |
A portion of amino acids 311-340 from the human protein was used as the immunogen for this STING antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the STING antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
STING (TMEM173) |
| Short name: |
STING Antibody (TMEM173) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
STING (Antibody to) (transmembrane protein 173) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Plasma membranes, TMEM173 and IDBG-47893 and ENSG00000184584 and 340061, TMEM173 and IDBG-646026 and ENSBTAG00000002296 and 533661, Tmem173 and IDBG-137341 and ENSMUSG00000024349 and 72512, cyclic-GMP-AMP binding, this GO :0002218 and activation of innate immune response and biological process this GO :0002230 and positive regulation of defense response to virus by host and biological process this GO :0005515 and protein binding and molecular function this GO :0005741 and mitochondrial outer membrane and cellular component this GO :0005777 and peroxisome and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006915 and apoptotic process and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0019901 and protein kinase binding and molecular function this GO :0030659 and cytoplasmic vesicle membrane and cellular component this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032092 and positive regulation of protein binding and biological process this GO :0032479 and regulation of type I interferon production and biological process this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0032608 and interferon-beta production and biological process this GO :0033160 and positive regulation of protein import into nucleus, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding and also this GO :0019901 : protein kinase binding and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0035438 : cyclic-di-GMP binding and also this GO :0042802 : identical protein binding and also this GO :0042803 : protein homodimerization activity and also this GO :0061507 : cyclic-GMP-AMP binding, this GO :0008134 : transcription factor binding, this GO :0019901 : protein kinase binding, this GO :0031625 : ubiquitin protein ligase binding, this GO :0035438 : cyclic-di-GMP binding, this GO :0042802 : identical protein binding, this GO :0042803 : protein homodimerization activity, this GO :0061507 : cyclic-GMP-AMP binding, translocation and biological process this GO :0035438 and cyclic-di-GMP binding and molecular function this GO :0035458 and cellular response to interferon-beta and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0042993 and positive regulation of transcription factor import into nucleus and biological process this GO :0045087 and innate immune response and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0051607 and defense response to virus and biological process this GO :0061507 and cyclic-GMP-AMP binding and molecular function this GO :0071360 and cellular response to exogenous dsRNA and biological process, transmembrane protein 173 |
| Identity: |
27962 |
| Gene: |
TMEM173 |
More about : TMEM173 |
| Long gene name: |
transmembrane protein 173 |
| Synonyms: |
FLJ38577 NET23 ERIS MPYS STING MITA |
| Synonyms name: |
stimulator of interferon genes |
| Locus: |
5q31, 2 |
| Discovery year: |
2006-08-24 |
| Entrez gene record: |
340061 |
| Pubmed identfication: |
21947006 |
| RefSeq identity: |
NM_198282 |
| Havana BLAST/BLAT: |
OTTHUMG00000129239 |