| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CCR3 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, FACS, WB |
| Recommended dilutions: |
Flow Cytometry: 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the CCR3 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This CCR3 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P51677 |
| Purity: |
Antigen affinity |
| Description: |
It belongs to family 1 of the G protein-coupled receptors, It is also known to be an entry co-receptor for HIV-1, It is highly expressed in eosinophils and basophils, MCP-3 (CCL7), MCP-4 (CCL13), This receptor binds and responds to a variety of chemokines, This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway, and RANTES (CCL5), and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells, eotaxin-3 (CCL26), including eotaxin (CCL11), CCR3 is a receptor for C-C type chemokines |
| Immunogen: |
A portion of amino acids 291-318 from the human protein was used as the immunogen for this CCR3 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CCR3 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CCR3 |
| Short name: |
CCR3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
chemokine (C-C motif) receptor 3 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, C-C chemokine receptor activity, CC-CKR-3 and CD193 and CKR3 and CMKBR3, CCR3 and IDBG-30125 and ENSG00000183625 and 1232, Ccr3 and IDBG-206550 and ENSMUSG00000035448 and 12771, Plasma membranes, this GO :0001938 and positive regulation of endothelial cell proliferation and biological process this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004950 and chemokine receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0006968 and cellular defense response and biological process this GO :0007155 and cell adhesion and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007188 and adenylate cyclase-modulating G-protein coupled receptor signaling pathway and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0016493 and C-C chemokine receptor activity and molecular function this GO :0045087 and innate immune response and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process, this GO :0004930 : G-protein coupled receptor activity, this GO :0004930 : G-protein coupled receptor activity and also this GO :0004950 : chemokine receptor activity and also this GO :0005515 : protein binding and also this GO :0016493 : C-C chemokine receptor activity, this GO :0004950 : chemokine receptor activity, this GO :0005515 : protein binding, this GO :0016493 : C-C chemokine receptor activity, 28967 and IDBG-647811 and ENSBTAG00000001338 and 408018, chemokine (C-C motif) receptor 3 |
| Identity: |
1604 |
| Gene: |
CCR3 |
More about : CCR3 |
| Long gene name: |
C-C motif chemokine receptor 3 |
| Synonyms gene: |
CMKBR3 |
| Synonyms gene name: |
chemokine (C-C motif) receptor 3 |
| Synonyms: |
CC-CKR-3 CKR3 CD193 |
| Locus: |
3p21, 31 |
| Discovery year: |
1995-05-30 |
| GenBank acession: |
AF247361 |
| Entrez gene record: |
1232 |
| Classification: |
CD molecules C-C motif chemokine receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000133484 |