| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
SOCS1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, FACS, IF, IHC, WB |
| Recommended dilutions: |
Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000-2000 |
| Notes: |
Titration of the SOCS1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This SOCS1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O15524 |
| Purity: |
Purified |
| Description: |
SSI family members are cytokine-inducible negative regulators of cytokine signaling, also known as suppressor of cytokine signaling(SOCS), family, SOCS1 is a member of the STAT-induced STAT inhibitor (SSI) |
| Immunogen: |
A portion of amino acids 35-66 from the human protein was used as the immunogen for this SOCS1 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the SOCS1 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
SOCS1 |
| Short name: |
SOCS1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
suppressor on cytokine signaling 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CIS1 and CISH1 and JAB and SOCS-1 and SSI-1 and SSI1 and TIP3, SOCS1 and IDBG-14621 and ENSG00000185338 and 8651, SOCS1 and IDBG-648701 and ENSBTAG00000004386 and 518795, Socs1 and IDBG-132667 and ENSMUSG00000038037 and 12703, nuclei, protein kinase binding, this GO :0001932 and regulation of protein phosphorylation and biological process this GO :0004860 and protein kinase inhibitor activity and molecular function this GO :0005159 and insulin-like growth factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006469 and negative regulation of protein kinase activity and biological process this GO :0007259 and JAK-STAT cascade and biological process this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0016567 and protein ubiquitination and biological process this GO :0019210 and kinase inhibitor activity and molecular function this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0035556 and intracellular signal transduction and biological process this GO :0040008 and regulation of growth and biological process this GO :0042518 and negative regulation of tyrosine phosphorylation of Stat3 protein and biological process this GO :0045087 and innate immune response and biological process this GO :0045444 and fat cell differentiation and biological process this GO :0046426 and negative regulation of JAK-STAT cascade and biological process this GO :0046627 and negative regulation of insulin receptor signaling pathway and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0060334 and regulation of interferon-gamma-mediated signaling pathway and biological process this GO :0060337 and type I interferon signaling pathway and biological process this GO :0060338 and regulation of type I interferon-mediated signaling pathway and biological process this GO :0060397 and JAK-STAT cascade involved in growth hormone signaling pathway and biological process this GO :0071230 and cellular response to amino acid stimulus and biological process, this GO :0004860 : protein kinase inhibitor activity, this GO :0004860 : protein kinase inhibitor activity and also this GO :0005159 : insulin-like growth factor receptor binding and also this GO :0005515 : protein binding and also this GO :0019210 : kinase inhibitor activity and also this GO :0019901 : protein kinase binding, this GO :0005159 : insulin-like growth factor receptor binding, this GO :0005515 : protein binding, this GO :0019210 : kinase inhibitor activity, this GO :0019901 : protein kinase binding, suppressor of cytokine signaling 1 |
| Identity: |
19383 |
| Gene: |
SOCS1 |
More about : SOCS1 |
| Long gene name: |
suppressor of cytokine signaling 1 |
| Synonyms: |
SOCS-1 SSI-1 JAB TIP3 Cish1 |
| Locus: |
16p13, 13 |
| Discovery year: |
2002-11-13 |
| GenBank acession: |
U88326 |
| Pubmed identfication: |
7796808 9266833 |
| Classification: |
Suppressors of cytokine signaling SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000129792 |