| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
BMI1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IF, IHC, WB, FACS |
| Recommended dilutions: |
Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the BMI1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This BMI1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P35226 |
| Purity: |
Antigen affinity |
| Description: |
In the PRC1 complex, PcG PRC1 complex acts via chromatin remodeling and modification of histones, [UniProt], a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility, throughout development, Component of the Polycomb group (PcG) multiprotein PRC1 complex |
| Immunogen: |
This BMI1 antibody was produced from rabbits immunized with BMI1 recombinant protein |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the BMI1 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
BMI1 |
| Short name: |
BMI1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
BMI1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1066 |
| Gene: |
BMI1 |
More about : BMI1 |
| Long gene name: |
BMI1 proto-oncogene, polycomb ring finger |
| Synonyms gene: |
PCGF4 |
| Synonyms gene name: |
polycomb group ring finger 4 B lymphoma Mo-MLV insertion region 1 homolog (mouse) |
| Synonyms: |
RNF51 |
| Locus: |
10p12, 2 |
| Discovery year: |
1994-01-05 |
| GenBank acession: |
BC011652 |
| Entrez gene record: |
648 |
| Pubmed identfication: |
8268912 |
| RefSeq identity: |
NM_005180 |
| Classification: |
Polycomb group ring fingers Ring finger proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000017807 |