| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
NIK (Nck-interacting kinase) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the NIK antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This NIK antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O95819 |
| Purity: |
Purified |
| Description: |
Expression appears to be ubiquitous, HGK/NIK binds, Isoform 5 appears to be more abundant in the brain, It appears to act upstream of the JUN N-terminal pathway, This protein is thought to interact with the SH3 domain of the adapter proteins Nck, a member of the STE20 subfamily of Ser/Thr protein kinases, and isoform 4 is predominant in the liver, expressed in all tissue types examined, may play a role in the response to environmental stress and cytokines such as TNF-alpha, skeletal muscle and placenta, to the N-terminal region of SPG3A, via its CNH regulatory domain, HGK/NIK |
| Immunogen: |
A portion of amino acids 618-649 from the human protein was used as the immunogen for this NIK antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the NIK antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
NIK (Nck-interacting kinase) |
| Short name: |
NIK Antibody (Nck-interacting kinase) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
NIK (Antibody to) (Nck-interacting phosphorylation catalyst) |
| Alternative technique: |
antibodies |
| Identity: |
6866 |
| Gene: |
MAP4K4 |
More about : MAP4K4 |
| Long gene name: |
mitogen-activated protein kinase kinase kinase kinase 4 |
| Synonyms: |
HGK NIK FLH21957 |
| Synonyms name: |
HPK/GCK-like kinase hepatocyte progenitor kinase-like/germinal center kinase-like kinase |
| Locus: |
2q11, 2 |
| Discovery year: |
1999-09-07 |
| GenBank acession: |
AF096300 |
| Entrez gene record: |
9448 |
| Pubmed identfication: |
9890973 9734811 9135144 |
| RefSeq identity: |
NM_004834 |
| Classification: |
Mitogen-activated protein kinase kinase kinase kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000155394 |