| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
PAK6 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the PAK6 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This PAK6 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9NQU5 |
| Purity: |
Purified |
| Description: |
PAK kinases are implicated in the regulation of a number of cellular processes, PAK6 was found to interact with androgen receptor (AR), The p21-activated protein kinase 6 gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen, The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, apoptosis and the MAP kinase signaling pathway, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain, including cytoskeleton rearrangement, which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development, The PAK6 protein shares a high degree of sequence similarity with p21-activated kinase (PAK) family members |
| Immunogen: |
A portion of amino acids 116-146 from the human protein was used as the immunogen for this PAK6 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the PAK6 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
PAK6 |
| Short name: |
PAK6 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PAK6 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16061 |
| Gene: |
PAK6 |
More about : PAK6 |
| Long gene name: |
p21 (RAC1) activated kinase 6 |
| Synonyms gene name: |
p21(CDKN1A)-activated kinase 6 p21 protein (Cdc42/Rac)-activated kinase 6 |
| Synonyms: |
PAK5 |
| Locus: |
15q15, 1 |
| Discovery year: |
2001-07-12 |
| GenBank acession: |
AF276893 |
| Entrez gene record: |
56924 |
| Pubmed identfication: |
11278661 |
| Havana BLAST/BLAT: |
OTTHUMG00000129921 |