| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
NRAS |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, FACS, IF, WB |
| Recommended dilutions: |
Flow Cytometry: 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the NRAS antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This NRAS antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P01111 |
| Purity: |
Purified |
| Description: |
Defects in the gene encoding this protein are a cause of juvenile myelomonocytic leukemia (JMML), This protein, This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex, is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor, which has intrinsic GTPase activity, NRAS is a membrane protein that shuttles between the Golgi apparatus and the plasma membrane |
| Immunogen: |
A portion of amino acids 72-101 from the human protein was used as the immunogen for this NRAS antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the NRAS antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
NRAS |
| Short name: |
NRAS Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
NRAS (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7989 |
| Gene: |
NRAS |
More about : NRAS |
| Long gene name: |
neuroblastoma RAS viral oncogene homolog |
| Synonyms gene name: |
neuroblastoma RAS viral (v-ras) oncogene homolog |
| Synonyms: |
N-ras |
| Locus: |
1p13, 2 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
BC005219 |
| Entrez gene record: |
4893 |
| RefSeq identity: |
NM_002524 |
| Classification: |
RAS type GTPase family |
| Havana BLAST/BLAT: |
OTTHUMG00000012059 |
| Locus Specific Databases: |
NRASbase: Mutation registry for autoimmune lymphoproliferative syndrome type IV LRG_92 |