| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
c-Abl |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IF, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the c-Abl antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This c-Abl antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P00519 |
| Purity: |
Purified |
| Description: |
The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, and stress response, cell adhesion, cell division, suggesting a cell cycle function for ABL1, ABL1 is a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation |
| Immunogen: |
A portion of amino acids 741-769 from the human protein was used as the immunogen for this c-Abl antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the c-Abl antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
c-Abl |
| Short name: |
c-Abl Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
c-Abl (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
76 |
| Gene: |
ABL1 |
More about : ABL1 |
| Long gene name: |
ABL proto-oncogene 1, non-receptor tyrosine kinase |
| Synonyms gene: |
ABL |
| Synonyms gene name: |
non-receptor tyrosine kinase , receptor tyrosine kinase c-abl oncogene 1, v-abl Abelson murine leukemia viral oncogene homolog 1 c-abl oncogene 1 |
| Synonyms: |
JTK7 c-ABL p150 |
| Locus: |
9q34, 12 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M14752 |
| Entrez gene record: |
25 |
| Pubmed identfication: |
1857987 12626632 |
| RefSeq identity: |
NM_007313 |
| Classification: |
SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000020813 |
| Locus Specific Databases: |
LRG_769 |