| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
NUR77 (NR4A1) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the NUR77 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This NUR77 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P22736 |
| Purity: |
Antigen affinity |
| Description: |
Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts, This protein acts as a nuclear transcription factor, Translocation of the protein from the nucleus to mitochondria induces apoptosis, NR4A1 is a member of the steroid-thyroid hormone-retinoid receptor superfamily |
| Immunogen: |
A portion of amino acids 329-358 from the human protein was used as the immunogen for this NUR77 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the NUR77 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
NUR77 (NR4A1) |
| Short name: |
NUR77 Antibody (NR4A1) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
family A, member 1), NUR77 (Antibody to) (nuclear receptor subfamily 4 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006367 and transcription initiation from RNA polymerase II promoter and biological process this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0010467 and gene expression and biological process this GO :0030522 and intracellular receptor signaling pathway and biological process this GO :0035767 and endothelial cell chemotaxis and biological process this GO :0035914 and skeletal muscle cell differentiation and biological process this GO :0035924 and cellular response to vascular endothelial growth factor stimulus and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043154 and negative regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043401 and steroid hormone mediated signaling pathway and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0044344 and cellular response to fibroblast growth factor stimulus and biological process this GO :0045087 and innate immune response and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0071310 and cellular response to organic substance and biological process, GFRP1 and HMR and N10 and NAK-1 and NGFIB and NP10 and NUR77 and TR3, NR4A1 and IDBG-33982 and ENSG00000123358 and 3164, NR4A1 and IDBG-632090 and ENSBTAG00000000507 and 528390, Nr4a1 and IDBG-185628 and ENSMUSG00000023034 and 15370, group A, member 1, nuclei, protein heterodimerization activity, this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001938 and positive regulation of endothelial cell proliferation and biological process this GO :0002042 and cell migration involved in sprouting angiogenesis and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003707 and steroid hormone receptor activity and molecular function this GO :0004879 and ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006351 and transcription, this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0003707 : steroid hormone receptor activity and also this GO :0004879 : ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0042803 : protein homodimerization activity and also this GO :0043565 : sequence-specific DNA binding and also this GO :0046982 : protein heterodimerization activity, this GO :0003677 : DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0003707 : steroid hormone receptor activity, this GO :0004879 : ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0042803 : protein homodimerization activity, this GO :0043565 : sequence-specific DNA binding, this GO :0046982 : protein heterodimerization activity, nuclear receptor subfamily 4 |
| Identity: |
7980 |
| Gene: |
NR4A1 |
More about : NR4A1 |
| Long gene name: |
nuclear receptor subfamily 4 group A member 1 |
| Synonyms gene: |
HMR GFRP1 |
| Synonyms gene name: |
group A, member 1 , nuclear receptor subfamily 4 |
| Synonyms: |
TR3 N10 NAK-1 NGFIB NUR77 |
| Locus: |
12q13 |
| Discovery year: |
1990-09-10 |
| GenBank acession: |
L13740 |
| Pubmed identfication: |
2626032 |
| Classification: |
Nuclear hormone receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000150393 |