| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Aryl Hydrocarbon Receptor (AHR) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, FACS, IF, IHC, WB |
| Recommended dilutions: |
Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the AHR antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This AHR antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P35869 |
| Purity: |
Antigen affinity |
| Description: |
Its ligands included a variety of aromatic hydrocarbons, This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450, [provided by RefSeq], AHR is a ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons |
| Immunogen: |
A portion of amino acids 555-582 from the human protein was used as the immunogen for this AHR antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the AHR antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Aryl Hydrocarbon Receptor (AHR) |
| Short name: |
Aryl Hydrocarbon Receptor Antibody (AHR) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Aryl Hydrocarbon Receptor (Antibody to) (aryl hydrocarbon receptor) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AHR and IDBG-629848 and ENSBTAG00000007746 and 280714, AHR and IDBG-8995 and ENSG00000106546 and 196, Ahr and IDBG-134957 and ENSMUSG00000019256 and 11622, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006805 and xenobiotic metabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0006950 and response to stress and biological process this GO :0007049 and cell cycle and biological process this GO :0007165 and signal transduction and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0009410 and response to xenobiotic stimulus and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0030522 and intracellular receptor signaling pathway and biological process this GO :0030850 and prostate gland development and biological process this GO :0030888 and regulation of B cell proliferation and biological process this GO :0032922 and circadian regulation of gene expression and biological process this GO :0034752 and cytosolic aryl hydrocarbon receptor complex and cellular component this GO :0035326 and enhancer binding and molecular function this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045899 and positive regulation of RNA polymerase II transcriptional preinitiation complex assembly and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0046983 and protein dimerization activity and molecular function this GO :0048608 and reproductive structure development and biological process this GO :0048732 and gland development and biological process this GO :0051879 and Hsp90 protein binding and molecular function this GO :0070888 and E-box binding and molecular function, E-box binding, bHLHe76, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001568 and blood vessel development and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003705 and RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0004879 and ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006355 and regulation of transcription, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0003705 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and also this GO :0004871 : signal transducer activity and also this GO :0004879 : ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding and also this GO :0035326 : enhancer binding and also this GO :0043565 : sequence-specific DNA binding and also this GO :0044212 : transcription regulatory region DNA binding and also this GO :0046982 : protein heterodimerization activity and also this GO :0046983 : protein dimerization activity and also this GO :0051879 : Hsp90 protein binding and also this GO :0070888 : E-box binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0003705 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, this GO :0004871 : signal transducer activity, this GO :0004879 : ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0005515 : protein binding, this GO :0008134 : transcription factor binding, this GO :0035326 : enhancer binding, this GO :0043565 : sequence-specific DNA binding, this GO :0044212 : transcription regulatory region DNA binding, this GO :0046982 : protein heterodimerization activity, this GO :0046983 : protein dimerization activity, this GO :0051879 : Hsp90 protein binding, this GO :0070888 : E-box binding, aryl hydrocarbon receptor |
| Identity: |
348 |
| Gene: |
AHR |
More about : AHR |
| Long gene name: |
aryl hydrocarbon receptor |
| Synonyms: |
bHLHe76 |
| Locus: |
7p21, 1 |
| Discovery year: |
1993-05-18 |
| GenBank acession: |
L19872 |
| Entrez gene record: |
196 |
| Pubmed identfication: |
8125016 |
| RefSeq identity: |
NM_001621 |
| Classification: |
Basic helix-loop-helix proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000149967 |