| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
AXIN2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, FACS, IHC, WB |
| Recommended dilutions: |
Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes: |
Titration of the AXIN2 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This AXIN2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9Y2T1 |
| Purity: |
Antigen affinity |
| Description: |
Apparently, Axin2, In mouse, Mutations in this gene have been associated with colorectal cancer with defective mismatch repair, The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, and conductin, and other tumors, beta-catenin, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), glycogen synthase kinase 3-beta, like its rodent homologs, mouse conductin/rat axil, neuroblastoma, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, the deregulation of beta-catenin is an important event in the genesis of a number of malignancies, which leads to the degradation of beta-catenin, The Axin-related protein |
| Immunogen: |
A portion of amino acids 816-843 from the human protein was used as the immunogen for this AXIN2 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the AXIN2 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
AXIN2 |
| Short name: |
AXIN2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
AXIN2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
904 |
| Gene: |
AXIN2 |
More about : AXIN2 |
| Long gene name: |
axin 2 |
| Synonyms: |
MGC126582 DKFZp781B0869 |
| Synonyms name: |
conductin axil |
| Locus: |
17q24, 1 |
| Discovery year: |
1998-09-17 |
| GenBank acession: |
AF078165 |
| Entrez gene record: |
8313 |
| Pubmed identfication: |
10049590 |
| RefSeq identity: |
NM_004655 |
| Havana BLAST/BLAT: |
OTTHUMG00000179353 |
| Locus Specific Databases: |
LRG_296 |