| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Phospho-S6K [p-p70S6K) (pS418) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, DB |
| Recommended dilutions: |
Dot blot: 1:500 |
| Notes: |
Titration of the phospho-S6K antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This phospho-S6K antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P23443 |
| Purity: |
Antigen affinity |
| Description: |
Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized, Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines, The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation, This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein, p70 S6K is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases |
| Immunogen: |
This phospho-S6K antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS418 of human RPS6KB1 |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the phospho-S6K antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Phospho-S6K [p-p70S6K) (pS418) |
| Short name: |
Phospho-S6K Antibody [p-p70S6K) (pS418) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
phosphorilated-S6K (Antibody to) [p-p70S6K) (pS418) |
| Alternative technique: |
antibodies |