| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Integrin beta 1 (ITGB1) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the Integrin beta 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This Integrin beta 1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P05556 |
| Purity: |
Antigen affinity |
| Description: |
At least 18 alpha and 8 beta subunits have been described in mammals, Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene, This gene encodes a beta subunit, hemostasis, immune response and metastatic diffusion of tumor cells, tissue repair, Integrins are heterodimeric proteins made up of alpha and beta subunits |
| Immunogen: |
A portion of amino acids 759-785 from the human protein was used as the immunogen for this Integrin beta 1 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Integrin beta 1 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Integrin beta 1 (ITGB1) |
| Short name: |
Integrin beta 1 Antibody (ITGB1) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MSK12)), antigen CD29 includes MDF2, b 1 (fibronectin receptor, b polypeptide, Integrin b 1 (Antibody to) (integrin |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD29 and FNRB and GPIIA and MDF2 and MSK12 and VLA-BETA and VLAB, Cell surfaces, ITGB1 and IDBG-637396 and ENSBTAG00000015910 and 281876, ITGB1 and IDBG-68302 and ENSG00000150093 and 3688, Itgb1 and IDBG-201159 and ENSMUSG00000025809 and 16412, MSK12), alpha-actinin binding, antigen CD29 includes MDF2, beta 1 (fibronectin receptor, beta polypeptide, this GO :0000082 and G1/S transition of mitotic cell cycle and biological process this GO :0001618 and virus receptor activity and molecular function this GO :0001669 and acrosomal vesicle and cellular component this GO :0001701 and in utero embryonic development and biological process this GO :0001708 and cell fate specification and biological process this GO :0001726 and ruffle and cellular component this GO :0001894 and tissue homeostasis and biological process this GO :0001948 and glycoprotein binding and molecular function this GO :0001968 and fibronectin binding and molecular function this GO :0002020 and protease binding and molecular function this GO :0002042 and cell migration involved in sprouting angiogenesis and biological process this GO :0003779 and actin binding and molecular function this GO :0004872 and receptor activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005518 and collagen binding and molecular function this GO :0005604 and basement membrane and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0005912 and adherens junction and cellular component this GO :0005925 and focal adhesion and cellular component this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0006968 and cellular defense response and biological process this GO :0007155 and cell adhesion and biological process this GO :0007156 and homophilic cell adhesion and biological process this GO :0007159 and leukocyte cell-cell adhesion and biological process this GO :0007160 and cell-matrix adhesion and biological process this GO :0007161 and calcium-independent cell-matrix adhesion and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007411 and axon guidance and biological process this GO :0007596 and blood coagulation and biological process this GO :0008277 and regulation of G-protein coupled receptor protein signaling pathway and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008305 and integrin complex and cellular component this GO :0008354 and germ cell migration and biological process this GO :0009615 and response to virus and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0010811 and positive regulation of cell-substrate adhesion and biological process this GO :0010976 and positive regulation of neuron projection development and biological process this GO :0014704 and intercalated disc and cellular component this GO :0014823 and response to activity and biological process this GO :0016020 and membrane and cellular component this GO :0016032 and viral process and biological process this GO :0016477 and cell migration and biological process this GO :0019900 and kinase binding and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0019904 and protein domain specific binding and molecular function this GO :0021943 and formation of radial glial scaffolds and biological process this GO :0030027 and lamellipodium and cellular component this GO :0030056 and hemidesmosome and cellular component this GO :0030175 and filopodium and cellular component this GO :0030183 and B cell differentiation and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0031175 and neuron projection development and biological process this GO :0031345 and negative regulation of cell projection organization and biological process this GO :0031589 and cell-substrate adhesion and biological process this GO :0031594 and neuromuscular junction and cellular component this GO :0031667 and response to nutrient levels and biological process this GO :0032154 and cleavage furrow and cellular component this GO :0032403 and protein complex binding and molecular function this GO :0032587 and ruffle membrane and cellular component this GO :0032594 and protein transport within lipid bilayer and biological process this GO :0033631 and cell-cell adhesion mediated by integrin and biological process this GO :0034329 and cell junction assembly and biological process this GO :0034667 and integrin alpha3-beta1 complex and cellular component this GO :0034677 and integrin alpha7-beta1 complex and cellular component this GO :0034678 and alpha8-beta1 integrin complex and cellular component this GO :0034679 and alpha9-beta1 integrin complex and cellular component this GO :0034698 and response to this GO nadotropin and biological process this GO :0035748 and myelin sheath abaxonal region and cellular component this GO :0042277 and peptide binding and molecular function this GO :0042383 and sarcolemma and cellular component this GO :0042470 and melanosome and cellular component this GO :0042493 and response to drug and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043235 and receptor complex and cellular component this GO :0043236 and laminin binding and molecular function this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045202 and synapse and cellular component this GO :0045214 and sarcomere organization and biological process this GO :0045596 and negative regulation of cell differentiation and biological process this GO :0045665 and negative regulation of neuron differentiation and biological process this GO :0045666 and positive regulation of neuron differentiation and biological process this GO :0045807 and positive regulation of endocytosis and biological process this GO :0046872 and metal ion binding and molecular function this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048675 and axon extension and biological process this GO :0048738 and cardiac muscle tissue development and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050776 and regulation of immune response and biological process this GO :0050839 and cell adhesion molecule binding and molecular function this GO :0050900 and leukocyte migration and biological process this GO :0051393 and alpha-actinin binding and molecular function this GO :0051726 and regulation of cell cycle and biological process this GO :0055007 and cardiac muscle cell differentiation and biological process this GO :0055037 and recycling endosome and cellular component this GO :0060135 and maternal process involved in female pregnancy and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070830 and tight junction assembly and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :0071305 and cellular response to vitamin D and biological process this GO :0071479 and cellular response to ionizing radiation and biological process this GO :0071559 and response to transforming growth factor beta and biological process this GO :2000811 and negative regulation of anoikis and biological process, this GO :0001618 : virus receptor activity, this GO :0001618 : virus receptor activity and also this GO :0001948 : glycoprotein binding and also this GO :0001968 : fibronectin binding and also this GO :0002020 : protease binding and also this GO :0003779 : actin binding and also this GO :0004872 : receptor activity and also this GO :0005102 : receptor binding and also this GO :0005178 : integrin binding and also this GO :0005515 : protein binding and also this GO :0005518 : collagen binding and also this GO :0019900 : kinase binding and also this GO :0019901 : protein kinase binding and also this GO :0019904 : protein domain specific binding and also this GO :0032403 : protein complex binding and also this GO :0042277 : peptide binding and also this GO :0043236 : laminin binding and also this GO :0046872 : metal ion binding and also this GO :0046982 : protein heterodimerization activity and also this GO :0050839 : cell adhesion molecule binding and also this GO :0051393 : alpha-actinin binding, this GO :0001948 : glycoprotein binding, this GO :0001968 : fibronectin binding, this GO :0002020 : protease binding, this GO :0003779 : actin binding, this GO :0004872 : receptor activity, this GO :0005102 : receptor binding, this GO :0005178 : integrin binding, this GO :0005515 : protein binding, this GO :0005518 : collagen binding, this GO :0019900 : kinase binding, this GO :0019901 : protein kinase binding, this GO :0019904 : protein domain specific binding, this GO :0032403 : protein complex binding, this GO :0042277 : peptide binding, this GO :0043236 : laminin binding, this GO :0046872 : metal ion binding, this GO :0046982 : protein heterodimerization activity, this GO :0050839 : cell adhesion molecule binding, this GO :0051393 : alpha-actinin binding, integrin |
| Identity: |
6153 |
| Gene: |
ITGB1 |
More about : ITGB1 |
| Long gene name: |
integrin subunit beta 1 |
| Synonyms gene: |
FNRB MSK12 MDF2 |
| Synonyms gene name: |
MSK12) , antigen CD29 includes MDF2, beta 1 (fibronectin receptor, beta polypeptide, integrin |
| Synonyms: |
CD29 GPIIA |
| Locus: |
10p11, 22 |
| Discovery year: |
1988-06-27 |
| GenBank acession: |
BC020057 |
| Entrez gene record: |
3688 |
| Pubmed identfication: |
2524991 |
| RefSeq identity: |
NM_002211 |
| Classification: |
Integrin beta subunits CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000017928 |