| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
OSCAR |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the OSCAR antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This OSCAR antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q8IYS5 |
| Purity: |
Antigen affinity |
| Description: |
Different from the other LRC members, Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts, OSCAR may be an important bone-specific regulator of osteoclast differentiation, This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex (LRC) protein family that plays critical roles in the regulation of both innate and adaptive immune responses, Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis |
| Immunogen: |
A portion of amino acids 205-231 from the human protein was used as the immunogen for this OSCAR antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the OSCAR antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
OSCAR |
| Short name: |
OSCAR Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
immunoglobulin-like receptor (Antibody to), osteoclast associated |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
OSCAR and IDBG-642249 and ENSBTAG00000001051 and 100336423, OSCAR and IDBG-67991 and ENSG00000170909 and 126014, Oscar and IDBG-135635 and ENSMUSG00000054594 and 232790, Plasma membranes, immunoglobulin-like receptor, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005515 : protein binding, this GO :0005515 : protein binding, osteoclast associated |
| Identity: |
29960 |
| Gene: |
OSCAR |
More about : OSCAR |
| Long gene name: |
immunoglobulin-like receptor , osteoclast associated |
| Locus: |
19q13, 42 |
| Discovery year: |
2007-06-21 |
| GenBank acession: |
AK130199 |
| Entrez gene record: |
126014 |
| Pubmed identfication: |
11805147 |
| RefSeq identity: |
NM_133169 |
| Classification: |
Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000064966 |