| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Anti-Bax |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the anti-Bax antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This anti-Bax antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q07812 |
| Purity: |
Antigen affinity |
| Description: |
BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities, Multiple alternatively spliced transcript variants, The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis, This protein forms a heterodimer with BCL2, This protein is reported to interact with, and functions as an apoptotic activator, and increase the opening of, have been reported for this gene, the mitochondrial voltage-dependent anion channel (VDAC), which encode different isoforms, which leads to the loss in membrane potential and the release of cytochrome c, The protein encoded by this gene belongs to the BCL2 protein family |
| Immunogen: |
A portion of amino acids 69-98 from the human protein was used as the immunogen for this anti-Bax antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the anti-Bax antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Bax |
| Short name: |
Anti-Bax Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
antibody to-BCL2-associated X protein (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11723 |
| Gene: |
TMBIM6 |
More about : TMBIM6 |
| Long gene name: |
transmembrane BAX inhibitor motif containing 6 |
| Synonyms gene: |
TEGT |
| Synonyms gene name: |
testis enhanced gene transcript |
| Synonyms: |
BI-1 BAXI1 |
| Synonyms name: |
BAX inhibitor 1 |
| Locus: |
12q13, 12 |
| Discovery year: |
1994-08-30 |
| GenBank acession: |
X75861 |
| Entrez gene record: |
7009 |
| Pubmed identfication: |
8530040 9660918 |
| RefSeq identity: |
NM_003217 |
| Classification: |
Transmembrane BAX inhibitor motif containing |
| Havana BLAST/BLAT: |
OTTHUMG00000169652 |