| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CD1b |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the CD1b antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This CD1b antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P29016 |
| Purity: |
Antigen affinity |
| Description: |
The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands, The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells, The human genome contains five CD1 family genes organized in a cluster on chromosome 1, The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, [provided by RefSeq], and requires vesicular acidification to bind lipid antigens, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin, This gene encodes a member of the CD1 family of transmembrane glycoproteins |
| Immunogen: |
A portion of amino acids 57-85 from the human protein was used as the immunogen for this CD1b antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CD1b antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CD1b |
| Short name: |
CD1b Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CD1b molecule (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1635 |
| Gene: |
CD1B |
More about : CD1B |
| Long gene name: |
CD1b molecule |
| Synonyms gene: |
CD1 |
| Synonyms gene name: |
CD1B antigen, b polypeptide CD1b antigen |
| Locus: |
1q23, 1 |
| Discovery year: |
1988-05-11 |
| GenBank acession: |
M28826 |
| Entrez gene record: |
910 |
| Pubmed identfication: |
2447586 |
| RefSeq identity: |
NM_001764 |
| Classification: |
C1-set domain containing CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000017513 |