| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CD68 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the CD68 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This CD68 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P34810 |
| Purity: |
Antigen affinity |
| Description: |
Alternative splicing results in multiple transcripts encoding different isoforms, It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family, It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins, Scavenger receptors typically function to clear cellular debris, The protein is also a member of the scavenger receptor family, The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface, and mediate the recruitment and activation of macrophages, promote phagocytosis, This gene encodes a 40~110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages |
| Immunogen: |
A portion of amino acids 209-237 from the human protein was used as the immunogen for this CD68 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CD68 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CD68 |
| Short name: |
CD68 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CD68 molecule (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD68 and IDBG-25923 and ENSG00000129226 and 968, CD68 and IDBG-635034 and ENSBTAG00000000133 and 504960, Cd68 and IDBG-191443 and ENSMUSG00000018774 and 12514, GP110 and LAMP4 and SCARD1, Plasma membranes, this GO :0005765 and lysosomal membrane and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0010008 and endosome membrane and cellular component this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0071310 and cellular response to organic substance and biological process, CD68 molecule |
| Identity: |
1693 |
| Gene: |
CD68 |
More about : CD68 |
| Long gene name: |
CD68 molecule |
| Synonyms gene name: |
CD68 antigen |
| Synonyms: |
SCARD1 macrosialin GP110 DKFZp686M18236 LAMP4 |
| Synonyms name: |
member 1 CD68 antigen macrophage antigen CD68 , scavenger receptor class D |
| Locus: |
17p13, 1 |
| Discovery year: |
1993-06-11 |
| GenBank acession: |
S57235 |
| Entrez gene record: |
968 |
| Pubmed identfication: |
9790779 |
| RefSeq identity: |
NM_001251 |
| Classification: |
CD molecules Scavenger receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000108146 |