| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Dclk1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the Dclk1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This Dclk1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9JLM8 |
| Purity: |
Antigen affinity |
| Description: |
Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been found, The encoded protein is involved in several different cellular processes, The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity, The protein encoded by this gene contains two N-terminal doublecortin domains, These variants encode different isoforms, This gene is up-regulated by brain-derived neurotrophic factor and associated with memory and general cognitive abilities, a C-terminal serine/threonine protein kinase domain, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, but the biological validity of some variants has not been determined, including neuronal migration, neuronal apoptosis and neurogenesis, retrograde transport, which are differentially expressed and have different kinase activities, which bind microtubules and regulate microtubule polymerization, which mediates multiple protein-protein interactions, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, This gene encodes a member of the protein kinase superfamily and the doublecortin family |
| Immunogen: |
A portion of amino acids 153-181 from the mouse protein was used as the immunogen for this Dclk1 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Dclk1 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Dclk1 |
| Short name: |
Dclk1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Dclk1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2700 |
| Gene: |
DCLK1 |
More about : DCLK1 |
| Long gene name: |
doublecortin like kinase 1 |
| Synonyms gene: |
DCAMKL1 |
| Synonyms gene name: |
doublecortin and CaM kinase-like 1 doublecortin-like kinase 1 |
| Synonyms: |
KIAA0369 DCLK DCDC3A |
| Locus: |
13q13, 3 |
| Discovery year: |
1999-02-22 |
| GenBank acession: |
AB002367 |
| Entrez gene record: |
9201 |
| Pubmed identfication: |
9747029 10036192 |
| RefSeq identity: |
NM_004734 |
| Classification: |
Doublecortin superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000016729 |