| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Rage |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the Rage antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This Rage antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9WVS4 |
| Purity: |
Antigen affinity |
| Description: |
AGE and HMGB1, Alzheimer's disease and even some tumors, Due to an enhanced level of RAGE ligands in diabetes or other chronic disorders, The interaction between RAGE and its ligands, [Wiki], is thought to result in pro-inflammatory gene activation, the 'receptor for advanced glycation endproducts' is a transmembrane receptor of the immunoglobulin super family, this receptor is hypothesised to have a causative effect in a range of inflammatory diseases such as diabetic complications, RAGE |
| Immunogen: |
A portion of amino acids 76-104 from the mouse protein was used as the immunogen for this Rage antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Rage antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Rage |
| Short name: |
Rage Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Rage (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
320 |
| Gene: |
AGER |
More about : AGER |
| Long gene name: |
advanced glycosylation end-product specific receptor |
| Synonyms: |
RAGE SCARJ1 |
| Synonyms name: |
receptor for advanced glycation end-products |
| Locus: |
6p21, 32 |
| Discovery year: |
1994-10-17 |
| GenBank acession: |
M91211 |
| Entrez gene record: |
177 |
| Pubmed identfication: |
7713518 |
| RefSeq identity: |
NM_001136 |
| Classification: |
C2-set domain containing Immunoglobulin like domain containing Scavenger receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000031120 |