| Alternative name 1: |
Clone: PR-4C6, Mab anti-, SOX2 |
| Alternative name 2: |
Clone: PR-4C6, Mab antibody-, SOX2 |
| Alternative name 3: |
Clone: PR-4C6, Mab antibody-, SOX2 |
| Alternative name 4: |
anti-SOX2 Clone: PR-4C6 |
| Alternative name 5: |
SOX2 Clone: PR-4C6 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal PR-4C6, SOX2 |
| Short name: |
Mouse Monoclonal antibody- Clone: PR-4C6, SOX2 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: PR-4C6, SRY (sex determining region Y)-box 2 |
| Alternative technique: |
murine |
| Alternative to gene target: |
ANOP3 and MCOPS3, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007605 and sensory perception of sound and biological process this GO :0009611 and response to wounding and biological process this GO :0010033 and response to organic substance and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0019827 and stem cell maintenance and biological process this GO :0021781 and glial cell fate commitment and biological process this GO :0021879 and forebrain neuron differentiation and biological process this GO :0021983 and pituitary gland development and biological process this GO :0021984 and adenohypophysis development and biological process this GO :0021987 and cerebral cortex development and biological process this GO :0022409 and positive regulation of cell-cell adhesion and biological process this GO :0030178 and negative regulation of Wnt signaling pathway and biological process this GO :0030539 and male genitalia development and biological process this GO :0030858 and positive regulation of epithelial cell differentiation and biological process this GO :0030900 and forebrain development and biological process this GO :0030910 and olfactory placode formation and biological process this GO :0032526 and response to retinoic acid and biological process this GO :0035019 and somatic stem cell maintenance and biological process this GO :0035198 and miRNA binding and molecular function this GO :0042246 and tissue regeneration and biological process this GO :0042472 and inner ear morphogenesis and biological process this GO :0043281 and regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0043586 and tongue development and biological process this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0044798 and nuclear transcription factor complex and cellular component this GO :0045165 and cell fate commitment and biological process this GO :0045596 and negative regulation of cell differentiation and biological process this GO :0045597 and positive regulation of cell differentiation and biological process this GO :0045665 and negative regulation of neuron differentiation and biological process this GO :0045666 and positive regulation of neuron differentiation and biological process this GO :0045668 and negative regulation of osteoblast differentiation and biological process this GO :0045747 and positive regulation of Notch signaling pathway and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046148 and pigment biosynthetic process and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048286 and lung alveolus development and biological process this GO :0048568 and embryonic organ development and biological process this GO :0048646 and anatomical structure formation involved in morphogenesis and biological process this GO :0048663 and neuron fate commitment and biological process this GO :0048839 and inner ear development and biological process this GO :0048852 and diencephalon morphogenesis and biological process this GO :0048863 and stem cell differentiation and biological process this GO :0050680 and negative regulation of epithelial cell proliferation and biological process this GO :0050767 and regulation of neurogenesis and biological process this GO :0050910 and detection of mechanical stimulus involved in sensory perception of sound and biological process this GO :0050973 and detection of mechanical stimulus involved in equilibrioception and biological process this GO :0060042 and retina morphogenesis in camera-type eye and biological process this GO :0060235 and lens induction in camera-type eye and biological process this GO :0060441 and epithelial tube branching involved in lung morphogenesis and biological process this GO :0070848 and response to growth factor and biological process this GO :0090090 and negative regulation of canonical Wnt signaling pathway and biological process this GO :0097150 and neuronal stem cell maintenance and biological process, SOX2 and IDBG-647279 and ENSBTAG00000011598 and 784383, SOX2 and IDBG-66692 and ENSG00000181449 and 6657, Sox2 and IDBG-137912 and ENSMUSG00000074637 and 20674, nuclei, protein heterodimerization activity, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000976 and transcription regulatory region sequence-specific DNA binding and molecular function this GO :0000981 and sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001649 and osteoblast differentiation and biological process this GO :0001654 and eye development and biological process this GO :0001708 and cell fate specification and biological process this GO :0001714 and endodermal cell fate specification and biological process this GO :0002052 and positive regulation of neuroblast proliferation and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006325 and chromatin organization and biological process this GO :0006351 and transcription, this GO :0000976 : transcription regulatory region sequence-specific DNA binding, this GO :0000976 : transcription regulatory region sequence-specific DNA binding and also this GO :0000981 : sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0003677 : DNA binding and also this GO :0003682 : chromatin binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0035198 : miRNA binding and also this GO :0043565 : sequence-specific DNA binding and also this GO :0044212 : transcription regulatory region DNA binding and also this GO :0046982 : protein heterodimerization activity, this GO :0000981 : sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0003677 : DNA binding, this GO :0003682 : chromatin binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0035198 : miRNA binding, this GO :0043565 : sequence-specific DNA binding, this GO :0044212 : transcription regulatory region DNA binding, this GO :0046982 : protein heterodimerization activity, SRY (sex determining region Y)-box 2 |
| Identity: |
11195 |
| Gene: |
SOX2 |
More about : SOX2 |
| Long gene name: |
SRY-box 2 |
| Synonyms gene name: |
SRY (sex determining region Y)-box 2 SRY box 2 |
| Locus: |
3q26, 33 |
| Discovery year: |
1993-11-30 |
| GenBank acession: |
BC013923 |
| Entrez gene record: |
6657 |
| Pubmed identfication: |
7849401 |
| RefSeq identity: |
NM_003106 |
| Classification: |
SRY-boxes |
| Havana BLAST/BLAT: |
OTTHUMG00000158222 |
| Locus Specific Databases: |
LOVD LRG_719 |