| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
DR4 (Death Receptor 4) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the DR4 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This DR4 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O00220 |
| Purity: |
Antigen affinity |
| Description: |
Studies with FADD-deficient mice suggested that FADD, This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), a death domain containing adaptor protein, and thus transduces cell death signal and induces cell apoptosis, is required for the apoptosis mediated by this protein, The protein encoded by this gene is a member of the TNF-receptor superfamily |
| Immunogen: |
A portion of amino acids 418-446 from the human protein was used as the immunogen for this DR4 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the DR4 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
DR4 (Death Receptor 4) |
| Short name: |
DR4 Antibody (Death Receptor 4) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
DR4 (Antibody to) (Death Receptor 4) |
| Alternative technique: |
antibodies |
| Identity: |
11904 |
| Gene: |
TNFRSF10A |
More about : TNFRSF10A |
| Long gene name: |
TNF receptor superfamily member 10a |
| Synonyms gene name: |
member 10a , tumor necrosis factor receptor superfamily |
| Synonyms: |
DR4 Apo2 TRAILR-1 CD261 |
| Locus: |
8p21, 3 |
| Discovery year: |
1998-12-04 |
| GenBank acession: |
U90875 |
| Entrez gene record: |
8797 |
| Pubmed identfication: |
9311998 9082980 |
| RefSeq identity: |
NM_003844 |
| Classification: |
CD molecules Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000097843 |