| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
NFATC4 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB, IF |
| Recommended dilutions: |
Immunofluorescence: 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the NFATC4 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This NFATC4 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q14934 |
| Purity: |
Antigen affinity |
| Description: |
Alternatively spliced transcript variants encoding different isoforms have been noted for this gene, Other members of this family of nuclear factors of activated T cells also participate in the formation of this complex, The product of this gene plays a role in the inducible expression of cytokine genes in T cells, This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component, [provided by RefSeq], especially in the induction of the IL-2 and IL-4, The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex |
| Immunogen: |
A portion of amino acids 744-773 from the human protein was used as the immunogen for this NFATC4 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the NFATC4 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
NFATC4 |
| Short name: |
NFATC4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
calcineurin-dependent 4 (Antibody to), cytoplasmic, nuclear factor on activated T-cells |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006954 and inflammatory response and biological process this GO :0007507 and heart development and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008630 and intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0034644 and cellular response to UV and biological process this GO :0042975 and peroxisome proliferator activated receptor binding and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045111 and intermediate filament cytoskeleton and cellular component this GO :0045333 and cellular respiration and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048167 and regulation of synaptic plasticity and biological process this GO :0051145 and smooth muscle cell differentiation and biological process this GO :0055001 and muscle cell development and biological process this GO :0071285 and cellular response to lithium ion and biological process this GO :2001235 and positive regulation of apoptotic signaling pathway and biological process, NF-AT3 and NF-ATC4 and NFAT3, NFATC4 and IDBG-3927 and ENSG00000100968 and 4776, NFATC4 and IDBG-645671 and ENSBTAG00000006366 and, Nfatc4 and IDBG-166063 and ENSMUSG00000023411 and 73181, calcineurin-dependent 4, cytoplasmic, nuclei, peroxisome proliferator activated receptor binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0000981 and sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0001078 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and molecular function this GO :0001569 and patterning of blood vessels and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003713 and transcription coactivator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006355 and regulation of transcription, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0000981 : sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0001078 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and also this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0003713 : transcription coactivator activity and also this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding and also this GO :0042975 : peroxisome proliferator activated receptor binding, this GO :0000981 : sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0001078 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, this GO :0003677 : DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0003713 : transcription coactivator activity, this GO :0005515 : protein binding, this GO :0008134 : transcription factor binding, this GO :0042975 : peroxisome proliferator activated receptor binding, nuclear factor of activated T-cells |
| Identity: |
7778 |
| Gene: |
NFATC4 |
More about : NFATC4 |
| Long gene name: |
nuclear factor of activated T-cells 4 |
| Synonyms gene name: |
calcineurin-dependent 4 , cytoplasmic, nuclear factor of activated T-cells |
| Synonyms: |
NFAT3 |
| Locus: |
14q12 |
| Discovery year: |
1994-11-16 |
| GenBank acession: |
BC053855 |
| Entrez gene record: |
4776 |
| Pubmed identfication: |
7749981 |
| RefSeq identity: |
NM_004554 |
| Classification: |
Nuclear factors of activated T-cells |
| Havana BLAST/BLAT: |
OTTHUMG00000029351 |