| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
ZEB2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, FACS, WB |
| Recommended dilutions: |
Flow Cytometry: 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the ZEB2 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This ZEB2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O60315 |
| Purity: |
Antigen affinity |
| Description: |
Alternatively spliced transcript variants have been found for this gene, It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs, Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome, The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins |
| Immunogen: |
A portion of amino acids 1078-1105 from the human protein was used as the immunogen for this ZEB2 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the ZEB2 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
ZEB2 |
| Short name: |
ZEB2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
zinc finger E-box binding homeobox 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0007399 and nervous system development and biological process this GO :0007417 and central nervous system development and biological process this GO :0019208 and phosphatase regulator activity and molecular function this GO :0021766 and hippocampus development and biological process this GO :0021846 and cell proliferation in forebrain and biological process this GO :0030177 and positive regulation of Wnt signaling pathway and biological process this GO :0043507 and positive regulation of JUN kinase activity and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045636 and positive regulation of melanocyte differentiation and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048023 and positive regulation of melanin biosynthetic process and biological process this GO :0048066 and developmental pigmentation and biological process this GO :0048598 and embryonic morphogenesis and biological process this GO :0070412 and R-SMAD binding and molecular function this GO :0097324 and melanocyte migration and biological process this GO :1903056 and regulation of melanosome organization and biological process, HSPC082 and SIP-1 and SIP1 and SMADIP1 and ZFHX1B, R-SMAD binding, ZEB2 and IDBG-71713 and ENSG00000169554 and 9839, Zeb2 and IDBG-168224 and ENSMUSG00000026872 and 24136, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001755 and neural crest cell migration and biological process this GO :0001756 and somitogenesis and biological process this GO :0001843 and neural tube closure and biological process this GO :0003676 and nucleic acid binding and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005634 and nucleus and cellular component this GO :0006351 and transcription, this GO :0003676 : nucleic acid binding, this GO :0003676 : nucleic acid binding and also this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0019208 : phosphatase regulator activity and also this GO :0043565 : sequence-specific DNA binding and also this GO :0046872 : metal ion binding and also this GO :0070412 : R-SMAD binding, this GO :0003677 : DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0019208 : phosphatase regulator activity, this GO :0043565 : sequence-specific DNA binding, this GO :0046872 : metal ion binding, this GO :0070412 : R-SMAD binding, 99328 and IDBG-642115 and ENSBTAG00000012615 and, zinc finger E-box binding homeobox 2 |
| Identity: |
14881 |
| Gene: |
ZEB2 |
More about : ZEB2 |
| Long gene name: |
zinc finger E-box binding homeobox 2 |
| Synonyms gene: |
ZFHX1B |
| Synonyms gene name: |
zinc finger homeobox 1b |
| Synonyms: |
KIAA0569 SIP-1 SIP1 |
| Synonyms name: |
SMAD interacting protein 1 |
| Locus: |
2q22, 3 |
| Discovery year: |
2001-03-14 |
| GenBank acession: |
AB011141 |
| Entrez gene record: |
9839 |
| RefSeq identity: |
NM_014795 |
| Classification: |
ZF class homeoboxes and pseudogenes Zinc fingers C2H2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000187624 |