MeCP2 Antibody

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Catalog number: F41828-0.4ML
Price: 406 €
Supplier: NJS poly
Product name: MeCP2 Antibody
Quantity: 0.4 ml
Other quantities: 0.08 ml 199€ 0.4 ml 406€ 1 vial 521€ 1 x 1 vial 411€
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Category: Antibody
Concentration: pH 7, with 0, 09% sodium azide, 4, In 1X PBS
Form: Antigen affinity purified
Conjugation: Unconjugated
Clone: Polyclonal antibody
Recognised antigen: MeCP2
Host animal: Rabbit (Oryctolagus cuniculus)
Clonality: Polyclonal (rabbit origin)
Species reactivity: Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications: ELISA, FACS, IHC, WB
Recommended dilutions: Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:50-1:100, Western blot: 1:1000
Notes: Titration of the MeCP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented use: This MeCP2 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #: P51608
Purity: Antigen affinity
Description: Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, It can bind specifically to a single methyl-CpG pair, It is not influenced by sequences flanking the methyl-CpGs, Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A, [UniProt], with a preference for 5-methylcytosine (5mC), MeCP2 is a chromosomal protein that binds to methylated DNA
Immunogen: A portion of amino acids 58-87 from the human protein was used as the immunogen for this MeCP2 antibody
Storage: Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the MeCP2 antibody and store frozen at -20 deg
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target: MeCP2
Short name: MeCP2 Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: MeCP2 (Antibody to)
Alternative technique: antibodies
Identity: 10470
Gene: RTT | More about : RTT
Long gene name: methyl-CpG binding protein 2
Synonyms gene: MRX16 MRX79
Synonyms gene name: X-linked 16 mental retardation, X-linked 79 Rett syndrome methyl CpG binding protein 2 (Rett syndrome) methyl CpG binding protein 2 , mental retardation
Synonyms: MECP2
Locus: Xq28
Discovery year: 1996-09-03
GenBank acession: AF158180
Entrez gene record: 4204
Pubmed identfication: 1606614 10508514
RefSeq identity: NM_004992
Classification: X-linked mental retardation Methyl-CpG binding domain containing
Havana BLAST/BLAT: OTTHUMG00000024229
Locus Specific Databases: RettBASE Mental Retardation database LRG_764

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