XRCC5 Antibody

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Catalog number: F41815-0.4ML
Price: 406 €
Supplier: NJS poly
Product name: XRCC5 Antibody
Quantity: 0.4 ml
Other quantities: 0.08 ml 199€ 1 vial 411€ 100ug 370€
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Category: Antibody
Concentration: pH 7, with 0, 09% sodium azide, 4, In 1X PBS
Form: Antigen affinity purified
Conjugation: Unconjugated
Clone: Polyclonal antibody
Recognised antigen: XRCC5
Host animal: Rabbit (Oryctolagus cuniculus)
Clonality: Polyclonal (rabbit origin)
Species reactivity: Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications: ELISA, FACS, WB, IF
Recommended dilutions: Flow Cytometry: 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000
Notes: Titration of the XRCC5 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented use: This XRCC5 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #: P13010
Purity: Antigen affinity
Description: A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity, Ku is the DNA-binding component of the DNA-dependent protein kinase, This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events, The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5
Immunogen: A portion of amino acids 424-450 from the human protein was used as the immunogen for this XRCC5 antibody
Storage: Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the XRCC5 antibody and store frozen at -20 deg
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target: XRCC5
Short name: XRCC5 Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) (Antibody to)
Alternative technique: antibodies
Alternative to gene target: BT, DNA-templated and biological process this GO :0007420 and brain development and biological process this GO :0008022 and protein C-terminus binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0016020 and membrane and cellular component this GO :0016032 and viral process and biological process this GO :0016817 and hydrolase activity, DNA-templated and biological process this GO :0050769 and positive regulation of neurogenesis and biological process this GO :0051575 and 5'-deoxyribose-5-phosphate lyase activity and molecular function this GO :0060218 and hematopoietic stem cell differentiation and biological process this GO :0070419 and nonhomolo this GO us end joining complex and cellular component this GO :0071398 and cellular response to fatty acid and biological process this GO :0071475 and cellular hyperosmotic salinity response and biological process this GO :0071481 and cellular response to X-ray and biological process this GO :0075713 and establishment of integrated proviral latency and biological process, KARP-1 and KARP1 and KU80 and Ku86 and KUB2 and NFIV, XRCC5 and IDBG-80616 and ENSG00000079246 and 7520, Xrcc5 and IDBG-165686 and ENSMUSG00000026187 and 22596, acting on acid anhydrides, acting on acid anhydrides and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0042162 : telomeric DNA binding and also this GO :0044212 : transcription regulatory region DNA binding and also this GO :0044822 : poly(A) RNA binding and also this GO :0051575 : 5'-deoxyribose-5-phosphate lyase activity, acting on acid anhydrides and molecular function this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0032508 and DNA duplex unwinding and biological process this GO :0042162 and telomeric DNA binding and molecular function this GO :0042493 and response to drug and biological process this GO :0043234 and protein complex and cellular component this GO :0043564 and Ku70:Ku80 complex and cellular component this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045892 and negative regulation of transcription, hydrolase activity, nuclei, telomeric region and cellular component this GO :0003677 and DNA binding and molecular function this GO :0003684 and damaged DNA binding and molecular function this GO :0003690 and double-stranded DNA binding and molecular function this GO :0003691 and double-stranded telomeric DNA binding and molecular function this GO :0004003 and ATP-dependent DNA helicase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006281 and DNA repair and biological process this GO :0006302 and double-strand break repair and biological process this GO :0006303 and double-strand break repair via nonhomolo this GO us end joining and biological process this GO :0006310 and DNA recombination and biological process this GO :0006351 and transcription, this GO :0000723 and telomere maintenance and biological process this GO :0000783 and nuclear telomere cap complex and cellular component this GO :0000784 and nuclear chromosome, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0003684 : damaged DNA binding and also this GO :0003690 : double-stranded DNA binding and also this GO :0003691 : double-stranded telomeric DNA binding and also this GO :0004003 : ATP-dependent DNA helicase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0008022 : protein C-terminus binding and also this GO :0016817 : hydrolase activity, this GO :0003684 : damaged DNA binding, this GO :0003690 : double-stranded DNA binding, this GO :0003691 : double-stranded telomeric DNA binding, this GO :0004003 : ATP-dependent DNA helicase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0008022 : protein C-terminus binding, this GO :0016817 : hydrolase activity, this GO :0031625 : ubiquitin protein ligase binding, this GO :0042162 : telomeric DNA binding, this GO :0044212 : transcription regulatory region DNA binding, this GO :0044822 : poly(A) RNA binding, this GO :0051575 : 5'-deoxyribose-5-phosphate lyase activity, 88138 and IDBG-643715 and ENSBTAG00000010426 and 531945, X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
Identity: 12833
Gene: XRCC5 | More about : XRCC5
Long gene name: X-ray repair cross complementing 5
Synonyms gene name: 80kD) , Ku autoantigen, X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining
Synonyms: KU80 KARP-1 Ku86 KUB2
Synonyms name: 80kDa , Ku autoantigen
Locus: 2q35
Discovery year: 1992-01-22
GenBank acession: AF039597
Entrez gene record: 7520
Pubmed identfication: 9636207 9214634
RefSeq identity: NM_021141
Havana BLAST/BLAT: OTTHUMG00000133059

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