SOCS4 Antibody

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Catalog number: F41736-0.4ML
Price: 406 €
Supplier: NJS poly
Product name: SOCS4 Antibody
Quantity: 0.4 ml
Other quantities: 0.08 ml 199€ 0.1mg 406€ 0.4 ml 406€
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Category: Antibody
Concentration: pH 7, with 0, 09% sodium azide, 4, In 1X PBS
Form: Antigen affinity purified
Conjugation: Unconjugated
Clone: Polyclonal antibody
Recognised antigen: SOCS4
Host animal: Rabbit (Oryctolagus cuniculus)
Clonality: Polyclonal (rabbit origin)
Species reactivity: Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications: ELISA, IF, WB, IHC
Recommended dilutions: IHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000
Notes: Titration of the SOCS4 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented use: This SOCS4 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #: Q8WXH5
Purity: Antigen affinity
Description: Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR, Substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins, [UniProt], SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction
Immunogen: A portion of amino acids 227-254 from the human protein was used as the immunogen for this SOCS4 antibody
Storage: Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the SOCS4 antibody and store frozen at -20 deg
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target: SOCS4
Short name: SOCS4 Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: suppressor on cytokine signaling 4 (Antibody to)
Alternative technique: antibodies
Alternative to gene target: SOCS4 and IDBG-646714 and ENSBTAG00000021988 and 540412, SOCS4 and IDBG-7209 and ENSG00000180008 and 122809, Socs4 and IDBG-154333 and ENSMUSG00000048379 and 67296, multiple, this GO :0007175 and negative regulation of epidermal growth factor-activated receptor activity and biological process this GO :0016567 and protein ubiquitination and biological process this GO :0032436 and positive regulation of proteasomal ubiquitin-dependent protein catabolic process and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0040008 and regulation of growth and biological process, suppressor of cytokine signaling 4
Identity: 19392
Gene: SOCS4 | More about : SOCS4
Long gene name: suppressor of cytokine signaling 4
Synonyms gene: SOCS7
Synonyms gene name: suppressor of cytokine signaling 7
Locus: 14q22, 3
Discovery year: 2002-11-11
GenBank acession: AF424815
Entrez gene record: 122809
Pubmed identfication: 12076535 10500304
Classification: Suppressors of cytokine signaling SH2 domain containing
Havana BLAST/BLAT: OTTHUMG00000140311

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