| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
PAX5 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, FACS, IHC, WB |
| Recommended dilutions: |
Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the PAX5 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This PAX5 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q02548 |
| Purity: |
Antigen affinity |
| Description: |
Alternatively spliced transcript variants encoding different isoforms have been described but their biological validity has not been determined, Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis, PAX proteins are important regulators in early development, The central feature of this gene family is a novel, This gene encodes the B-cell lineage specific activator protein that is expressed at early, This gene is located at 9p13, This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, and alterations in the expression of their genes are thought to contribute to neoplastic transformation, and in derived large-cell lymphomas, but not late stages of B-cell differentiation, highly conserved DNA-binding motif, known as the paired box, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas, which is involved in t(9, 14)(p13, This gene encodes a member of the paired box (PAX) family of transcription factors, q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype |
| Immunogen: |
A portion of amino acids 178-207 from the human protein was used as the immunogen for this PAX5 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the PAX5 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
PAX5 |
| Short name: |
PAX5 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PAX5 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8619 |
| Gene: |
PAX5 |
More about : PAX5 |
| Long gene name: |
paired box 5 |
| Synonyms gene name: |
paired box gene 5 (B-cell lineage specific activator protein) paired box gene 5 (B-cell lineage specific activator) |
| Synonyms: |
BSAP |
| Synonyms name: |
B-cell lineage specific activator |
| Locus: |
9p13, 2 |
| Discovery year: |
1992-11-03 |
| Entrez gene record: |
5079 |
| Pubmed identfication: |
1516825 8431641 |
| Classification: |
PRD class homeoboxes and pseudogenes Paired boxes |
| Havana BLAST/BLAT: |
OTTHUMG00000019907 |