HDAC6 Antibody

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Catalog number: F41165-0.4ML
Price: 406 €
Supplier: NJS poly
Product name: HDAC6 Antibody
Quantity: 0.4 ml
Other quantities: 0.08 ml 199€ 0.1mg 389€ 0.1ml 263€ 1 tube 486€ 1 vial 521€ 1 x 1 vial 486€ 100ul 707€
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Category: Antibody
Concentration: pH 7, with 0, 09% sodium azide, 4, In 1X PBS
Form: Purified
Conjugation: Unconjugated
Clone: Polyclonal antibody
Recognised antigen: HDAC6
Host animal: Rabbit (Oryctolagus cuniculus)
Clonality: Polyclonal (rabbit origin)
Species reactivity: Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications: ELISA, WB, IHC
Recommended dilutions: IHC (Paraffin): 1:10-1:50, Western blot: 1:1000
Notes: Titration of the HDAC6 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented use: This HDAC6 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #: Q9UBN7
Purity: Purified
Description: H2B, H3 and H4), HDAC is also a potential target of sumoylation, HDAC6 is ubiquitinated, HDAC6 plays a central role in microtubule-dependent cell motility via deacetylation of tubulin, Histone deacetylases act via the formation of large multiprotein complexes, Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, SIRT2, and F-actin, and has been shown to interact with HDAC11, but its polyubiquitination however does not lead to degradation, cell cycle progression and developmental events, HDAC6 (histone deacetylase 6) is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A
Immunogen: A portion of amino acids 1182-1215 from the human protein was used as the immunogen for this HDAC6 antibody
Storage: Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the HDAC6 antibody and store frozen at -20 deg
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target: HDAC6
Short name: HDAC6 Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: histone deacetylase 6 (Antibody to)
Alternative technique: antibodies
Alternative to gene target: BT, CPBHM and HD6 and PPP1R90, DNA-templated and biological process this GO :0006476 and protein deacetylation and biological process this GO :0006511 and ubiquitin-dependent protein catabolic process and biological process this GO :0006515 and misfolded or incompletely synthesized protein catabolic process and biological process this GO :0006886 and intracellular protein transport and biological process this GO :0007026 and negative regulation of microtubule depolymerization and biological process this GO :0008013 and beta-catenin binding and molecular function this GO :0008017 and microtubule binding and molecular function this GO :0008152 and metabolic process and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0009636 and response to toxic substance and biological process this GO :0009967 and positive regulation of signal transduction and biological process this GO :0010033 and response to organic substance and biological process this GO :0010469 and regulation of receptor activity and biological process this GO :0010634 and positive regulation of epithelial cell migration and biological process this GO :0010727 and negative regulation of hydrogen peroxide metabolic process and biological process this GO :0010870 and positive regulation of receptor biosynthetic process and biological process this GO :0016234 and inclusion body and cellular component this GO :0016235 and aggresome and cellular component this GO :0016236 and macroautophagy and biological process this GO :0016575 and histone deacetylation and biological process this GO :0016787 and hydrolase activity and molecular function this GO :0019899 and enzyme binding and molecular function this GO :0030286 and dynein complex and cellular component this GO :0030424 and axon and cellular component this GO :0030425 and dendrite and cellular component this GO :0031252 and cell leading edge and cellular component this GO :0031593 and polyubiquitin binding and molecular function this GO :0032041 and NAD-dependent histone deacetylase activity (H3-K14 specific) and molecular function this GO :0032418 and lysosome localization and biological process this GO :0034983 and peptidyl-lysine deacetylation and biological process this GO :0035967 and cellular response to topologically incorrect protein and biological process this GO :0042826 and histone deacetylase binding and molecular function this GO :0042903 and tubulin deacetylase activity and molecular function this GO :0043014 and alpha-tubulin binding and molecular function this GO :0043130 and ubiquitin binding and molecular function this GO :0043162 and ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway and biological process this GO :0043204 and perikaryon and cellular component this GO :0043234 and protein complex and cellular component this GO :0043241 and protein complex disassembly and biological process this GO :0043242 and negative regulation of protein complex disassembly and biological process this GO :0045861 and negative regulation of proteolysis and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0046969 and NAD-dependent histone deacetylase activity (H3-K9 specific) and molecular function this GO :0046970 and NAD-dependent histone deacetylase activity (H4-K16 specific) and molecular function this GO :0048156 and tau protein binding and molecular function this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0048487 and beta-tubulin binding and molecular function this GO :0051354 and negative regulation of oxidoreductase activity and biological process this GO :0051788 and response to misfolded protein and biological process this GO :0051879 and Hsp90 protein binding and molecular function this GO :0060632 and regulation of microtubule-based movement and biological process this GO :0060765 and regulation of androgen receptor signaling pathway and biological process this GO :0070201 and regulation of establishment of protein localization and biological process this GO :0070301 and cellular response to hydrogen peroxide and biological process this GO :0070840 and dynein complex binding and molecular function this GO :0070842 and aggresome assembly and biological process this GO :0070845 and polyubiquitinated misfolded protein transport and biological process this GO :0070846 and Hsp90 deacetylation and biological process this GO :0070848 and response to growth factor and biological process this GO :0070932 and histone H3 deacetylation and biological process this GO :0070933 and histone H4 deacetylation and biological process this GO :0071218 and cellular response to misfolded protein and biological process this GO :0090035 and positive regulation of chaperone-mediated protein complex assembly and biological process this GO :0090042 and tubulin deacetylation and biological process this GO :0097372 and NAD-dependent histone deacetylase activity (H3-K18 specific) and molecular function this GO :1901300 and positive regulation of hydrogen peroxide-mediated programmed cell death and biological process, HDAC6 and IDBG-63929 and ENSG00000094631 and 10013, Hdac6 and IDBG-129835 and ENSMUSG00000031161 and 15185, NAD-dependent histone deacetylase activity (H3-K18 specific), nuclei, this GO :0000118 and histone deacetylase complex and cellular component this GO :0000209 and protein polyubiquitination and biological process this GO :0003779 and actin binding and molecular function this GO :0004407 and histone deacetylase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005874 and microtubule and cellular component this GO :0005875 and microtubule associated complex and cellular component this GO :0005881 and cytoplasmic microtubule and cellular component this GO :0005901 and caveola and cellular component this GO :0006351 and transcription, this GO :0003779 : actin binding, this GO :0003779 : actin binding and also this GO :0004407 : histone deacetylase activity and also this GO :0005515 : protein binding and also this GO :0008013 : beta-catenin binding and also this GO :0008017 : microtubule binding and also this GO :0008270 : zinc ion binding and also this GO :0016787 : hydrolase activity and also this GO :0019899 : enzyme binding and also this GO :0031593 : polyubiquitin binding and also this GO :0032041 : NAD-dependent histone deacetylase activity (H3-K14 specific) and also this GO :0042826 : histone deacetylase binding and also this GO :0042903 : tubulin deacetylase activity and also this GO :0043014 : alpha-tubulin binding and also this GO :0043130 : ubiquitin binding and also this GO :0046969 : NAD-dependent histone deacetylase activity (H3-K9 specific) and also this GO :0046970 : NAD-dependent histone deacetylase activity (H4-K16 specific) and also this GO :0048156 : tau protein binding and also this GO :0048487 : beta-tubulin binding and also this GO :0051879 : Hsp90 protein binding and also this GO :0070840 : dynein complex binding and also this GO :0097372 : NAD-dependent histone deacetylase activity (H3-K18 specific), this GO :0004407 : histone deacetylase activity, this GO :0005515 : protein binding, this GO :0008013 : beta-catenin binding, this GO :0008017 : microtubule binding, this GO :0008270 : zinc ion binding, this GO :0016787 : hydrolase activity, this GO :0019899 : enzyme binding, this GO :0031593 : polyubiquitin binding, this GO :0032041 : NAD-dependent histone deacetylase activity (H3-K14 specific), this GO :0042826 : histone deacetylase binding, this GO :0042903 : tubulin deacetylase activity, this GO :0043014 : alpha-tubulin binding, this GO :0043130 : ubiquitin binding, this GO :0046969 : NAD-dependent histone deacetylase activity (H3-K9 specific), this GO :0046970 : NAD-dependent histone deacetylase activity (H4-K16 specific), this GO :0048156 : tau protein binding, this GO :0048487 : beta-tubulin binding, this GO :0051879 : Hsp90 protein binding, this GO :0070840 : dynein complex binding, this GO :0097372 : NAD-dependent histone deacetylase activity (H3-K18 specific), 76413 and IDBG-636881 and ENSBTAG00000013244 and 513602, histone deacetylase 6
Identity: 14064
Gene: HDAC6 | More about : HDAC6
Long gene name: histone deacetylase 6
Synonyms: KIAA0901 JM21 HD6 FLJ16239 PPP1R90
Synonyms name: protein phosphatase 1, regulatory subunit 90
Locus: Xp11, 23
Discovery year: 2000-11-28
GenBank acession: AF132609
Entrez gene record: 10013
Pubmed identfication: 10220385 10048485
RefSeq identity: NM_006044
Classification: Histone deacetylases, class IIB Protein phosphatase 1 regulatory subunits
Havana BLAST/BLAT: OTTHUMG00000034496
Locus Specific Databases: Mental Retardation database

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