| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CD11b |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, FACS, WB, IHC |
| Recommended dilutions: |
Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes: |
Titration of the CD11b antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This CD11b antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P11215 |
| Purity: |
Antigen affinity |
| Description: |
Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain, The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), and also in the phagocytosis of complement coated particles, or inactivated-C3b (iC3b) receptor 3 ('CR3'), CD11b is the integrin alpha M chain |
| Immunogen: |
A portion of amino acids 253-282 from the human protein was used as the immunogen for this CD11b antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CD11b antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CD11b |
| Short name: |
CD11b Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CD11b (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1626 |
| Gene: |
CD11B |
More about : CD11B |
| Long gene name: |
integrin subunit alpha M |
| Synonyms gene: |
CR3A |
| Synonyms gene name: |
alpha, alpha M (complement component 3 receptor 3 subunit) , alpha M (complement component receptor 3, also known as CD11b (p170), integrin, macrophage antigen alpha polypeptide) integrin |
| Synonyms: |
MAC-1 CD11b ITGAM |
| Synonyms name: |
complement component 3 receptor 3 subunit |
| Locus: |
16p11, 2 |
| Discovery year: |
1988-08-05 |
| GenBank acession: |
J03925 |
| Entrez gene record: |
3684 |
| RefSeq identity: |
NM_000632 |
| Classification: |
Complement system Integrin alpha subunits CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000176612 |