| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Dnmt3a |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the Dnmt3a antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This Dnmt3a antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9Y6K1 |
| Purity: |
Antigen affinity |
| Description: |
Dnmt3a is a DNA methyltransferase that is thought to function in de novo methylation, Studies in mice have demonstrated that DNA methylation is required for mammalian development, The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated, [Wiki], and X-chromosome inactivation, imprinting, rather than maintenance methylation, CpG methylation is an epigenetic modification that is important for embryonic development |
| Immunogen: |
A portion of amino acids 457-486 from the human protein was used as the immunogen for this Dnmt3a antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Dnmt3a antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Dnmt3a |
| Short name: |
Dnmt3a Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Dnmt3a (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2978 |
| Gene: |
DNMT3A |
More about : DNMT3A |
| Long gene name: |
DNA methyltransferase 3 alpha |
| Synonyms gene name: |
DNA (cytosine-5-)-methyltransferase 3 alpha |
| Locus: |
2p23, 3 |
| Discovery year: |
1998-07-15 |
| Entrez gene record: |
1788 |
| Pubmed identfication: |
9662389 10433969 |
| RefSeq identity: |
NM_022552 |
| Classification: |
PWWP domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000094777 |
| Locus Specific Databases: |
LRG_459 |