| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
MUC1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the MUC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This MUC1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P15941 |
| Purity: |
Antigen affinity |
| Description: |
Binds, Can act both as an adhesion and an anti-adhesion protein, In activated T-cells, May provide a protective layer on epithelial cells against bacterial and enzyme attack, Modulates signaling in ERK, Promotes tumor progression, Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response, SRC and NF-kappa-B pathways, The beta subunit contains a C-terminal domain which is involved in cell signaling, [UniProt], influences directly or indirectly the Ras/MAPK pathway, the PE21 promoter element of TP53 and represses TP53 activity, through phosphorylations and protein-protein interactions, together with KLF4, The MUC1 alpha subunit has cell adhesive properties |
| Immunogen: |
A portion of amino acids 1202-1231 from the human protein was used as the immunogen for this MUC1 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the MUC1 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
MUC1 |
| Short name: |
MUC1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MUC1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7508 |
| Gene: |
MUC1 |
More about : MUC1 |
| Long gene name: |
cell surface associated , mucin 1 |
| Synonyms gene: |
PUM MCKD1 |
| Synonyms gene name: |
mucin 1, transmembrane medullary cystic kidney disease 1 (autosomal dominant) |
| Synonyms: |
CD227 PEM ADMCKD ADMCKD1 MCKD MCD |
| Locus: |
1q22 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
J05581 |
| Entrez gene record: |
4582 |
| Pubmed identfication: |
1697589 23396133 |
| RefSeq identity: |
NM_002456 |
| Classification: |
Mucins CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000035681 |