MUC1 Antibody (Mucin-1)

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Catalog number: F40466-0.08ML
Price: 199 €
Supplier: NJS poly
Product name: MUC1 Antibody (Mucin-1)
Quantity: 0.08 ml
Other quantities: 0.08 ml 199€
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Category: Antibody
Concentration: pH 7, with 0, 09% sodium azide, 4, In 1X PBS
Form: Antigen affinity purified
Conjugation: Unconjugated
Clone: Polyclonal antibody
Recognised antigen: MUC1 (Mucin-1)
Host animal: Rabbit (Oryctolagus cuniculus)
Clonality: Polyclonal (rabbit origin)
Species reactivity: Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications: ELISA, WB
Recommended dilutions: Western blot: 1:1000
Notes: Titration of the MUC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented use: This MUC1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #: P15941
Purity: Antigen affinity
Description: Binds, Can act both as an adhesion and an anti-adhesion protein, In activated T-cells, May provide a protective layer on epithelial cells against bacterial and enzyme attack, Modulates signaling in ERK, Promotes tumor progression, Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response, SRC and NF-kappa-B pathways, The beta subunit contains a C-terminal domain which is involved in cell signaling, [UniProt], influences directly or indirectly the Ras/MAPK pathway, the PE21 promoter element of TP53 and represses TP53 activity, through phosphorylations and protein-protein interactions, together with KLF4, The MUC1 alpha subunit has cell adhesive properties
Immunogen: A portion of amino acids 1202-1231 from the human protein was used as the immunogen for this MUC1 antibody
Storage: Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the MUC1 antibody and store frozen at -20 deg
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target: MUC1 (Mucin-1)
Short name: MUC1 Antibody (Mucin-1)
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: MUC1 (Antibody to) (Mucin-1)
Alternative technique: antibodies
Identity: 7508
Gene: MUC1 | More about : MUC1
Long gene name: cell surface associated , mucin 1
Synonyms gene: PUM MCKD1
Synonyms gene name: mucin 1, transmembrane medullary cystic kidney disease 1 (autosomal dominant)
Locus: 1q22
Discovery year: 1986-01-01
GenBank acession: J05581
Entrez gene record: 4582
Pubmed identfication: 1697589 23396133
RefSeq identity: NM_002456
Classification: Mucins CD molecules
Havana BLAST/BLAT: OTTHUMG00000035681

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