CD117 Antibody

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Catalog number: F40159-0.4ML
Price: 406 €
Supplier: NJS poly
Product name: CD117 Antibody
Quantity: 0.4 ml
Other quantities: 1 mililiter 779€ 1 vial 486€ 1 x 1 vial 602€ 100ug 448€ 500ug 818€
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Category: Antibody
Concentration: pH 7, with 0, 09% sodium azide, 4, In 1X PBS
Form: Antigen affinity purified
Conjugation: Unconjugated
Clone: Polyclonal antibody
Recognised antigen: CD117
Host animal: Rabbit (Oryctolagus cuniculus)
Clonality: Polyclonal (rabbit origin)
Species reactivity: Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications: ELISA, FACS, WB
Recommended dilutions: Flow Cytometry: 1:10-1:50, Western blot: 1:1000
Notes: Titration of the CD117 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented use: This CD117 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #: P10721
Purity: Antigen affinity
Description: Altered forms of this receptor may be associated with some types of cancer, It is a receptor tyrosine kinase type III, Signalling through CD117 plays a role in cell survival, When this receptor binds to stem cell factor (SCF) it forms a dimer that activates its intrinsic tyrosine kinase activity, [Wiki], also known as steel factor or c-kit ligand, and differentiation, proliferation, that in turn phosphorylates and activates signal transduction molecules that propagate the signal in the cell, which binds to stem cell factor (a substance that causes certain types of cells to grow), CD117 is a cytokine receptor expressed on the surface of hematopoietic stem cells as well as other cell types
Immunogen: A portion of amino acids 680-711 from the human protein was used as the immunogen for this CD117 antibody
Storage: Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CD117 antibody and store frozen at -20 deg
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target: CD117
Short name: CD117 Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: CD117 (Antibody to)
Alternative technique: antibodies
Identity: 6342
Gene: KIT | More about : KIT
Long gene name: KIT proto-oncogene receptor tyrosine kinase
Synonyms gene: PBT
Synonyms gene name: piebald trait v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Synonyms: CD117 SCFR C-Kit
Locus: 4q12
Discovery year: 1986-01-01
GenBank acession: S67773
Entrez gene record: 3815
Pubmed identfication: 9027509
RefSeq identity: NM_000222
Classification: CD molecules Immunoglobulin like domain containing Receptor Tyrosine Kinases
Havana BLAST/BLAT: OTTHUMG00000128713
Locus Specific Databases: LRG_307

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