| Category: |
Antibody |
| Concentration: |
09% sodium azide, 4 with 0, In 1X PBS pH 7 |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Bax |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IHC, WB, FACS |
| Recommended dilutions: |
Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes: |
Titration of the Bax antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This Bax antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q07812 |
| Purity: |
Purified |
| Description: |
BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities, Bax forms a heterodimer with BCL2, The expression of the Bax gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis, This protein is reported to interact with, and functions as an apoptotic activator, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c, Bax belongs to the BCL2 protein family |
| Immunogen: |
A portion of amino acids 41-76 (BH3 domain) from the human protein was used as the immunogen for this Bax antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Bax antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Bax |
| Short name: |
Bax Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
BCL2-associated X protein (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11723 |
| Gene: |
TMBIM6 |
More about : TMBIM6 |
| Long gene name: |
transmembrane BAX inhibitor motif containing 6 |
| Synonyms gene: |
TEGT |
| Synonyms gene name: |
testis enhanced gene transcript |
| Synonyms: |
BI-1 BAXI1 |
| Synonyms name: |
BAX inhibitor 1 |
| Locus: |
12q13, 12 |
| Discovery year: |
1994-08-30 |
| GenBank acession: |
X75861 |
| Entrez gene record: |
7009 |
| Pubmed identfication: |
8530040 9660918 |
| RefSeq identity: |
NM_003217 |
| Classification: |
Transmembrane BAX inhibitor motif containing |
| Havana BLAST/BLAT: |
OTTHUMG00000169652 |