| Gene info: |
(1996) described human PIN1 and showed that deletion of PIN1 from HeLa cells induces mitotic arrest, Lu et al, PIN1 is a member of a new class of peptidyl-prolyl cis/trans isomerases that includes the Escherichia coli parvulin, and Drosophila melanogaster dodo gene products, whereas HeLa cells overexpressing PIN1 arrest in the G2 phase, yeast ESS1, PIN1 is an essential nuclear peptidyl-prolyl cis/trans isomerase involved in the regulation of mitosis |
| Gene names: |
DOD, PPIase Pin1, Peptidyl-prolyl cis-trans isomerase Pin1, Prolyl isomerase, UBL5, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
| Antibodie's label: |
unlabelled serum |
| Purity: |
Immunoaffinity Purified |
| Ab raised in: |
Chicken |
| Type: |
Polyclonal |
| Antigen: |
1-163 |
| Immuno application: |
Western Blot |
| Antibody advice: |
Prolyl isomerase antibody can be used for the detection of Prolyl isomerase by Western Blot |
| Suspention, pH, azide: |
No preservatives added, Phosphate-Buffered Saline |
| Keep at: |
Antibodies should not be exposed to prolonged high temperatures, As with all antibodies care should be taken to avoid repeated freeze thaw cycles, Long term storage should be at -20 grades C, PIN1 antibody can be stored at 4 grades C for short term (weeks) |
| Works with: |
Human |
| Omim nr: |
5453898 |
| Ncbi nr: |
1, NP_006212 |
| KDa: |
2, 2 kDa (calculated) |
| Vial with antibody: |
in solution |
| Quantity per ml: |
1 mg/mL |
| NCBI GENE nr: |
5300 |
| GENE symbol: |
PIN1 |
| Antigene name: |
NIMA-interacting 1, peptidylprolyl cis/trans isomerase |
| Source: |
Homo sapiens |
| Protein nr: |
Q13526 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
PIN1 |
| Short name: |
anti-PIN1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
NIMA-interacting 1 (Antibody to), antibody to-peptidylprolyl cis/trans isomerase |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DOD and UBL5, NIMA-interacting 1, PIN1 and IDBG-26087 and ENSG00000127445 and 5300, PIN1 and IDBG-643081 and ENSBTAG00000016988 and 535470, nuclei, phosphothreonine binding, this GO :0000413 and protein peptidyl-prolyl isomerization and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0003755 and peptidyl-prolyl cis-trans isomerase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006457 and protein folding and biological process this GO :0007049 and cell cycle and biological process this GO :0007088 and regulation of mitosis and biological process this GO :0016607 and nuclear speck and cellular component this GO :0016853 and isomerase activity and molecular function this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0030496 and midbody and cellular component this GO :0030512 and negative regulation of transforming growth factor beta receptor signaling pathway and biological process this GO :0031434 and mitogen-activated protein kinase kinase binding and molecular function this GO :0032321 and positive regulation of Rho GTPase activity and biological process this GO :0032465 and regulation of cytokinesis and biological process this GO :0032480 and negative regulation of type I interferon production and biological process this GO :0032794 and GTPase activating protein binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0050815 and phosphoserine binding and molecular function this GO :0050816 and phosphothreonine binding and molecular function this GO :0051443 and positive regulation of ubiquitin-protein transferase activity and biological process this GO :0060393 and regulation of pathway-restricted SMAD protein phosphorylation and biological process this GO :0070373 and negative regulation of ERK1 and ERK2 cascade and biological process this GO :2000146 and negative regulation of cell motility and biological process, this GO :0003755 : peptidyl-prolyl cis-trans isomerase activity, this GO :0003755 : peptidyl-prolyl cis-trans isomerase activity and also this GO :0005515 : protein binding and also this GO :0016853 : isomerase activity and also this GO :0031434 : mitogen-activated protein kinase kinase binding and also this GO :0032794 : GTPase activating protein binding and also this GO :0050815 : phosphoserine binding and also this GO :0050816 : phosphothreonine binding, this GO :0005515 : protein binding, this GO :0016853 : isomerase activity, this GO :0031434 : mitogen-activated protein kinase kinase binding, this GO :0032794 : GTPase activating protein binding, this GO :0050815 : phosphoserine binding, this GO :0050816 : phosphothreonine binding, peptidylprolyl cis/trans isomerase |
| Identity: |
8988 |
| Gene: |
PIN1 |
More about : PIN1 |
| Long gene name: |
NIMA-interacting 1 , peptidylprolyl cis/trans isomerase |
| Synonyms gene name: |
protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 |
| Synonyms: |
dod |
| Locus: |
19p13 |
| Discovery year: |
1996-12-16 |
| Entrez gene record: |
5300 |
| Pubmed identfication: |
8606777 |
| Classification: |
Parvulins |
| Havana BLAST/BLAT: |
OTTHUMG00000180388 |
| Locus Specific Databases: |
LRG_847 |