| Gene info: |
<, <, <, <, A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity, Part of a complex consisting of RAD51B, RAD51 subfamily, RAD51C, RAD51D, This protein functionally complements Chinese hamster irs1SF, XRCC2 and XRCC3, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable, thought to repair chromosomal fragmentation, translocations and deletions, /b>, /b>, /b>, /b>, : Belongs to the recA family, : Interacts with RAD51C and RAD51, : Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, : Met-241 is associated with the development of cutaneous malignant melanoma, DISEASE<, FUNCTION<, SIMILARITY<, SUBUNIT<, This protein is a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage, b>, b>, b>, b> |
| Gene names: |
CMM6, X-ray repair cross-complementing protein 3, DNA repair protein XRCC3 |
| Antibodie's label: |
unlabelled serum |
| Purity: |
Immunoaffinity Purified |
| Ab raised in: |
Chicken |
| Type: |
Polyclonal |
| Antigen: |
213-346 |
| Immuno application: |
Western Blot, ELISA |
| Antibody advice: |
may also work for ICC and IHC, XRCC3 antibody can be used for the detection of DNA-repair protein XRCC3 by ELISA and Western Blot |
| Suspention, pH, azide: |
No preservatives added, Phosphate-Buffered Saline |
| Keep at: |
Antibodies should not be exposed to prolonged high temperatures, As with all antibodies care should be taken to avoid repeated freeze thaw cycles, Long term storage should be at -20 grades C, XRCC3 antibody can be stored at 4 grades C for short term (weeks) |
| Works with: |
Human |
| Omim nr: |
4885659 |
| Ncbi nr: |
1, NP_005423 |
| KDa: |
37, 9 kDa (calculated) |
| Vial with antibody: |
in solution |
| Quantity per ml: |
1 mg/mL |
| NCBI GENE nr: |
7517 |
| GENE symbol: |
XRCC3 |
| Antigene name: |
X-ray repair complementing defective repair in Chinese hamster cells 3 |
| Source: |
Homo sapiens |
| Protein nr: |
O43542 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
XRCC3 |
| Short name: |
anti-XRCC3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
antibody to-X-ray repair complementing defective repair in Chinese hamster cells 3 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CMM6, XRCC3 and IDBG-22058 and ENSG00000126215 and 7517, XRCC3 and IDBG-635474 and ENSBTAG00000009966 and 768244, Xrcc3 and IDBG-173748 and ENSMUSG00000021287 and 74335, crossover junction endodeoxyribonuclease activity, endonucleolytic and biological process this GO :0003677 and DNA binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005657 and replication fork and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0006200 and ATP catabolic process and biological process this GO :0006259 and DNA metabolic process and biological process this GO :0006281 and DNA repair and biological process this GO :0006310 and DNA recombination and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0008094 and DNA-dependent ATPase activity and molecular function this GO :0008821 and crossover junction endodeoxyribonuclease activity and molecular function this GO :0010033 and response to organic substance and biological process this GO :0010824 and regulation of centrosome duplication and biological process this GO :0033065 and Rad51C-XRCC3 complex and cellular component this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0071140 and resolution of mitotic recombination intermediates and biological process this GO :0090267 and positive regulation of mitotic cell cycle spindle assembly checkpoint and biological process, nuclei, this GO :0000400 and four-way junction DNA binding and molecular function this GO :0000724 and double-strand break repair via homolo this GO us recombination and biological process this GO :0000737 and DNA catabolic process, this GO :0000400 : four-way junction DNA binding, this GO :0000400 : four-way junction DNA binding and also this GO :0003677 : DNA binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0008094 : DNA-dependent ATPase activity and also this GO :0008821 : crossover junction endodeoxyribonuclease activity, this GO :0003677 : DNA binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0008094 : DNA-dependent ATPase activity, this GO :0008821 : crossover junction endodeoxyribonuclease activity, X-ray repair complementing defective repair in Chinese hamster cells 3 |
| Identity: |
12830 |
| Gene: |
XRCC3 |
More about : XRCC3 |
| Long gene name: |
X-ray repair cross complementing 3 |
| Synonyms gene name: |
X-ray repair complementing defective repair in Chinese hamster cells 3 |
| Synonyms name: |
RAD51-like |
| Locus: |
14q32, 3 |
| Discovery year: |
1995-08-11 |
| GenBank acession: |
AF035586 |
| Entrez gene record: |
7517 |
| Pubmed identfication: |
7603995 |
| RefSeq identity: |
NM_005432 |
| Havana BLAST/BLAT: |
OTTHUMG00000169228 |