| Gene info: |
&, IKK &, IKK is a serine protein kinase, NF-kB is associated with IkB proteins in the cell cytoplasm, The IkB kinase (IKK) phosphorylates IkB, and mediates IkB degradation and NF-kB activation, inhibitor of k light polypeptide gene enhancer in B-cells, kinase &, subunit, subunit is part of the IKK complex, which inhibit NF-kB activity, #946, #946, #946, #946, IkB kinase & |
| Gene names: |
I-kappa-B kinase 2, I-kappa-B-kinase beta, IKK-beta, IKK2, IKKB, IMD15, Inhibitor of nuclear factor kappa-B kinase subunit beta, NFKBIKB, IKKB |
| Antibodie's label: |
unlabelled serum |
| Purity: |
Antigen affinity-purified |
| Ab raised in: |
Chicken |
| Type: |
Polyclonal |
| Antigen: |
310-376 |
| Immuno application: |
Western Blot |
| Antibody advice: |
may also work for IHC and ICC, IKK2 antibody can be used for the detection of IKK2 by Western blot |
| Suspention, pH, azide: |
No preservatives added, Phosphate-Buffered Saline |
| Keep at: |
Antibodies should not be exposed to prolonged high temperatures, As with all antibodies care should be taken to avoid repeated freeze thaw cycles, Long term storage should be at -20 grades C, IKBKB antibody can be stored at 4 grades C for short term (weeks) |
| Works with: |
Mouse, Rat, Human |
| Omim nr: |
3213217 |
| Ncbi nr: |
1, AAC64675 |
| KDa: |
6 kDa (calculated), 86 |
| Vial with antibody: |
in solution |
| Quantity per ml: |
1 mg/mL |
| NCBI GENE nr: |
3551 |
| GENE symbol: |
IKBKB |
| Antigene name: |
kinase beta, inhibitor of kappa light polypeptide gene enhancer in B-cells |
| Source: |
Homo sapiens |
| Protein nr: |
O14920 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
IKBKB |
| Short name: |
anti-IKBKB Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
kinase b (Antibody to), antibody to-inhibitor on kappa light polypeptide gene enhancer in B-cells |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0070423 and nucleotide-binding oli this GO merization domain containing signaling pathway and biological process this GO :0071356 and cellular response to tumor necrosis factor and biological process this GO :0097110 and scaffold protein binding and molecular function this GO :2001259 and positive regulation of cation channel activity and biological process, IKBKB and IDBG-19987 and ENSG00000104365 and 3551, IKBKB and IDBG-629838 and ENSBTAG00000007599 and 281854, IKK-beta and IKK2 and IKKB and IMD15 and NFKBIKB, Ikbkb and IDBG-141021 and ENSMUSG00000031537 and 16150, alcohol group as acceptor, alcohol group as acceptor and also this GO :0019901 : protein kinase binding and also this GO :0042803 : protein homodimerization activity and also this GO :0046982 : protein heterodimerization activity and also this GO :0097110 : scaffold protein binding, alcohol group as acceptor and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034146 and toll-like receptor 5 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0034166 and toll-like receptor 10 signaling pathway and biological process this GO :0035631 and CD40 receptor complex and cellular component this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0035872 and nucleotide-binding domain, kinase beta, leucine rich repeat containing receptor signaling pathway and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0042501 and serine phosphorylation of STAT protein and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045893 and positive regulation of transcription, nuclei, this GO :0001782 and B cell homeostasis and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006954 and inflammatory response and biological process this GO :0007249 and I-kappaB kinase/NF-kappaB signaling and biological process this GO :0007252 and I-kappaB phosphorylation and biological process this GO :0008384 and IkappaB kinase activity and molecular function this GO :0008385 and IkappaB kinase complex and cellular component this GO :0009103 and lipopolysaccharide biosynthetic process and biological process this GO :0009615 and response to virus and biological process this GO :0009898 and cytoplasmic side of plasma membrane and cellular component this GO :0010765 and positive regulation of sodium ion transport and biological process this GO :0016020 and membrane and cellular component this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0008384 : IkappaB kinase activity and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0008384 : IkappaB kinase activity, this GO :0016772 : transferase activity, this GO :0016773 : phosphotransferase activity, this GO :0019901 : protein kinase binding, this GO :0042803 : protein homodimerization activity, this GO :0046982 : protein heterodimerization activity, this GO :0097110 : scaffold protein binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0016773 : phosphotransferase activity, transferring phosphorus-containing groups and molecular function this GO :0016773 and phosphotransferase activity, inhibitor of kappa light polypeptide gene enhancer in B-cells |
| Identity: |
5960 |
| Gene: |
IKBKB |
More about : IKBKB |
| Long gene name: |
inhibitor of nuclear factor kappa B kinase subunit beta |
| Synonyms gene name: |
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| Synonyms: |
IKK2 NFKBIKB IKK-beta IKKB |
| Locus: |
8p11, 21 |
| Discovery year: |
1998-02-11 |
| GenBank acession: |
AF029684 |
| Entrez gene record: |
3551 |
| Pubmed identfication: |
9878263 9763654 18308615 |
| Havana BLAST/BLAT: |
OTTHUMG00000164092 |