| Gene info: |
Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling, These cytokines produce their effects by binding to the Type 1 Interferon-alpha Receptor (IFNAR1), This down regulation is thought to be influenced by phosphorylation of Serine 535 and 539 in the IFNAR1, Interferons are widely used therapeutic agents because of their anti tumor and antiviral effects and because of their modulatory effects on the immune system |
| Gene names: |
Cytokine receptor class-II member 1, IFN-R-1, IFN-alpha-REC, IFNAR, IFNBR, IFRC, AVP |
| Antibodie's label: |
unlabelled serum |
| Purity: |
Affinity Purified |
| Ab raised in: |
Rabbit |
| Type: |
Polyclonal |
| Spicific to: |
539, Interferon a Receptor antibody is specific for IFNAR1 phosphorylated at Ser535 |
| Antigen: |
539 Type I Interferon-a Receptor Subunit 1 (IFNAR1), IFNAR1 (Ser535/539) polyclonal antibody was made against a synthetic phosphopeptide corresponding to amino acid residues surrounding the human Phospho-Ser535 |
| Immuno application: |
immuno-histo-chemistry, Western Blot |
| Antibody advice: |
Suitability for Immunohistochemistry (IHC) has not yet been determined, When internally tested under ideal conditions the working dilutions were 1:1000 for DB and WB, Applications include Dot Blots (DB) and Western Blots (WB) |
| Suspention, pH, azide: |
100 ug per mL BSA and 50% glycerol, 150 mM NaCl, 100 uL in 10 mM HEPES (pH 7, 5) |
| Keep at: |
Stable for one year, but shorter term storage at &ndash, 20 grades C is also acceptable as aliquots may be taken without freeze/thawing due to the presence of 50% glycerol, 80 grades C is recommended, For long term storage &ndash |
| Works with: |
Bovine, Mouse, Rat, Human |
| Omim nr: |
90110827 |
| Ncbi nr: |
P17181 |
| KDa: |
110-130 |
| Vial with antibody: |
in solution |
| NCBI GENE nr: |
3454 |
| GENE symbol: |
IFNAR1 |
| Antigene name: |
beta and omega) receptor 1, interferon (alpha |
| Source: |
Homo sapiens |
| Protein nr: |
P17181 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
Interferon-a Receptor (phospho Ser535 / 539) |
| Short name: |
anti-Interferon-a Receptor (phospho Ser535 / 539) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
antibody to-Interferon-a Receptor (phosphorilated Ser535 / 539) (Antibody to) |
| Alternative technique: |
antibodies |