| Gene info: |
In addition, In contrast, Phosphorylation of DARPP-32 is thought to play a critical role in the regulation of dopaminergic neurotransmission, The protein inhibits protein phosphatase I when it is phosphorylated on Thr34, a dopamine (DA) and cAMP-regulated ~32k phosphoprotein that is associated with dopaminoceptive neurons bearing D-1 receptors in the basal ganglia, caffeine and Prozac®, the activity of DARPP-32 is also thought to play important roles in the actions of alcohol, when DARPP-32 is phosphorylated on Thr75 the protein acts as an inhibitor of PKA, DARPP-32 |
| Gene names: |
DARPP-32, Darpp-32, Darpp32 |
| Antibodie's label: |
unlabelled serum |
| Purity: |
Affinity Purified |
| Ab raised in: |
Rabbit |
| Type: |
Polyclonal |
| Spicific to: |
DARPP 32 antibody is specific for the ~32k DARPP-32 phosphorylated at Thr34 |
| Antigen: |
DARPP-32 (Thr34) polyclonal antibody was made against a synthetic phosphopeptide corresponding to amino acids residues surrounding the phospho Thr34 of DARPP-32 |
| Immuno application: |
Western Blot |
| Antibody advice: |
Rabbit anti-DARPP-32 (Thr34) recognizes human, Suitability for Immunohistochemistry (IHC) has not yet been determined, When internally tested under ideal conditions the working dilutions were 1:1000 for DB and WB, and rat forms of the protein, mouse, Applications include Dot Blots (DB) and Western Blots (WB) |
| Suspention, pH, azide: |
100 ug per mL BSA and 50% glycerol, 150 mM NaCl, 100 uL in 10 mM HEPES (pH 7, 5) |
| Keep at: |
Stock solutions are stable for a minimum of 1 year at -20 grades C, but shorter term storage at -20 grades C is also acceptable as aliquots may be taken without freeze/thawing due to the presence of 50% glycerol, For long term storage -80 grades C is recommended |
| Works with: |
Mouse, Rat, Xenopus, Human |
| Omim nr: |
81884861 |
| Ncbi nr: |
Q6J4I0 |
| KDa: |
32 |
| Vial with antibody: |
in solution |
| NCBI GENE nr: |
360616 |
| GENE symbol: |
Ppp1r1b |
| Antigene name: |
regulatory (inhibitor) subunit 1B, protein phosphatase 1 |
| Source: |
Rattus norvegicus |
| Protein nr: |
Q6J4I0 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
DARPP 32 (phospho Thr34) |
| Short name: |
anti-DARPP 32 (phospho Thr34) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
antibody to-DARPP 32 (phosphorilated Thr34) (Antibody to) |
| Alternative technique: |
antibodies |