| Gene info: |
B cells and B cell lymphomas, Each IL acts on a specific, Human IL10 is a non glycosylated polypeptide consisting of 178 amino acids, IL10 enhances cytotoxic T cell development, IL10 inhibits cytokine production by macrophages and suppresses macrophage class II MHC expression, IL10 will stimulate the growth of stem cells, ILs have a variety of functions, The cellular sources of IL10 are CD4+ T cells and T cell clones, The human IL10 gene is on human chromosome, There is 73% homology between the human and mouse IL10 proteins, although some are produced by certain phagocytes and auxiliary cells, and costimulates B cell differentiation and immunoglobulin secretion, but most function to direct other immune cells to divide and differentiate, however, limited group of cells through a receptor specific for that IL, macrophages, mast cell lines and keratinocytes, mast cells and thymocytes, the human IL10 acts on both human and mouse target cells, thymocytes, while the mouse IL10 has species specific activity, Interleukins (ILs) are a large group of cytokines that are produced mainly by leukocytes |
| Gene names: |
Cytokine synthesis inhibitory factor, GVHDS, IL-10, IL10AInterleukin-10, TGIF, CSIF |
| Antibodie's label: |
unlabelled serum |
| Purity: |
Anti-hIL-10 specific antibody was purified by affinity chromatography employing immobilized hIL-10 matrix |
| Ab raised in: |
Rabbit |
| Type: |
Polyclonal |
| Antigen: |
98%) recombinant hIL-10 (human Interleukin-10), Produced from sera of rabbits pre-immunized with highly pure (> |
| Immuno application: |
NELISAut, Western Blot, ELISA |
| Antibody advice: |
ELISA: To detect hIL-10 by direct ELISA (using 100 &, Sandwich: To detect hIL-10 by sandwich ELISA (using 100 &, This antigen affinity purified antibody, This antigen affinity purified antibody, Used in conjunction with compatible secondary reagents the detection limit for recombinant hIL-10 is 1, Western Blot: To detect hIL-10 by Western Blot analysis this antibody can be used at a concentration of 0, a concentration of 4, allows the detection of 0, allows the detection of at least 0, in conjunction with compatible secondary reagents, in conjunction with our Biotinylated Anti-Human IL-10 (XP-5161Bt) as a detection antibody, under either reducing or non-reducing conditions, #956, #956, 0 ng/lane, 0 ug/mL of this antibody is required, 0 ug/mL of this antibody is required, 0-6, 1 - 0, 2 - 0, 2 - 0, 2 ug/mL, 4 ng/well of recombinant hIL-10, 4 ng/well of recombinant hIL-10, 5 - 2, 5 - 3, 5 ug/mL of this antibody is required, L/well antibody solution) a concentration of 0, L/well antibody solution) a concentration of at least 0, Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity of hIL-10 (30 ng/mL) |
| Keep at: |
Avoid repeated freeze-thaw cycles, Frozen aliquots are stable for at least 6 months when stored at -20 grades C, The reconstituted antibody is stable for at least two weeks at 2-8 grades C, IL-10 antibody is stable for at least 2 years from date of receipt at -20 grades C |
| Works with: |
Human |
| Omim nr: |
124292 |
| Ncbi nr: |
P22301 |
| Vial with antibody: |
Lyophilized |
| NCBI GENE nr: |
3586 |
| GENE symbol: |
IL10 |
| Antigene name: |
interleukin 10 |
| Source: |
Homo sapiens |
| Protein nr: |
P22301 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
IL-10 |
| Short name: |
anti-IL-10 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
antibody to-Interleukin-10 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
5962 |
| Gene: |
IL10 |
More about : IL10 |
| Long gene name: |
interleukin 10 |
| Synonyms: |
CSIF TGIF IL10A IL-10 |
| Synonyms name: |
cytokine synthesis inhibitory factor T-cell growth inhibitory factor |
| Locus: |
1q32, 1 |
| Discovery year: |
1991-10-31 |
| GenBank acession: |
M57627 |
| Entrez gene record: |
3586 |
| Pubmed identfication: |
9162098 |
| RefSeq identity: |
NM_000572 |
| Classification: |
Interleukins |
| Havana BLAST/BLAT: |
OTTHUMG00000036386 |