| Gene info: |
Binding of IFN gamma induces receptor dimerization, CDw119 serves as the IFN gamma binding chain and associates with the IFN gamma beta chain which is required for receptor signaling, Contains 2 fibronectin type III domains, Defects in IFN gamma Receptor beta are a cause of mendelian susceptibility to mycobacterial disease (MSMD), IFN gamma initiates and regulates a variety of immune responses and is required for signal transduction, It is also likely to interact with GAF, Jak1 and Jak2 protein kinase activation and, NK cells, STAT1 activation, The IFN gamma receptor beta chain is expressed on T and B cells, The extracellular portion of both the IFN gamma receptor alpha and beta chains must be species matched, This class II cytokine receptor pairs with CDw119 to form the IFN gamma receptor and is an integral part of the IFN gamma signal transduction pathway, a rare condition that confers predisposition to illness caused by several mycobacteria strains, and fibroblasts, internalization, monocytes/ macrophages, ultimately, IFN gamma receptor beta is part of the receptor for interferon gamma |
| Gene names: |
IFNG2Interferon gammaIFN-gamma |
| Antibodie's label: |
Biotin |
| Purity: |
Anti-Rat IFN-gamma specific antibody was purified by affinity chromatography and then biotinylated |
| Ab raised in: |
Goat |
| Type: |
Polyclonal |
| Antigen: |
98%) recombinant Rat IFN-gamma (Rat IFN-gamma), Produced from sera of goats pre-immunized with highly pure (> |
| Immuno application: |
Western Blot, ELISA |
| Antibody advice: |
(XP-5157) as a capture antibody, Sandwich: To detect Rat IFN-&, This biotinylated polyclonal antibody, Used in conjunction with compatible secondary reagents, Used in conjunction with compatible secondary reagents the detection limit for recombinant Rat IFN-&, Western Blot: To detect Rat IFN-&, allows the detection of at least 0, allows the detection of at least 0, by Western Blot analysis this antibody can be used at a concentration of 0, by direct ELISA (using 100 &, by sandwich ELISA (using 100 &, in conjunction with our Polyclonal Anti-Rat IFN-&, is 1, under either reducing or non-reducing conditions, #947, #947, #947, #947, #947, #947, #947, #956, #956, 0 ng/lane, 0 ug/mL of this antibody is required, 1 - 0, 15 - 0, 2 - 0, 2 ng/well of recombinant Rat IFN-&, 2 ug/mL, 25 - 1, 30 ug/mL, 4 ng/well of recombinant Rat IFN-&, 5 - 3, ELISA: To detect Rat IFN-&, L/well antibody solution) a concentration of 0, L/well antibody solution) this antibody can be used at a concentration of 0 |
| Keep at: |
Avoid repeated freeze-thaw cycles, Frozen aliquots are stable for at least 6 months when stored at -20 grades C, The reconstituted antibody is stable for at least two weeks at 2-8 grades C, IFN-gamma antibody is stable for at least 2 years from date of receipt at -20 grades C |
| Works with: |
Rat |
| Omim nr: |
124482 |
| Ncbi nr: |
P01581 |
| Vial with antibody: |
Lyophilized |
| NCBI GENE nr: |
25712 |
| GENE symbol: |
Ifng |
| Antigene name: |
interferon gamma |
| Source: |
Rattus norvegicustus norvegicus |
| Protein nr: |
P01581 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
IFN-gamma |
| Short name: |
anti-IFN-gamma Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
antibody to-Interferon-g (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
5417 |
| Gene: |
IFNA1 |
More about : IFNA1 |
| Long gene name: |
interferon alpha 1 |
| Synonyms: |
IFNA@ IFL IFN IFN-ALPHA IFNA13 IFN-alphaD |
| Synonyms name: |
IFN-alpha 1b interferon alpha 1b |
| Locus: |
9p21, 3 |
| Discovery year: |
1993-01-14 |
| Entrez gene record: |
3439 |
| Pubmed identfication: |
1385305 |
| RefSeq identity: |
NM_024013 |
| Classification: |
Interferons |
| Havana BLAST/BLAT: |
OTTHUMG00000019673 |