| Gene info: |
CNTF itself lacks a classical signal peptide sequence of a secreted protein, CNTF stimulates gene expression, but is thought to convey its cytoprotective effects after release from adult glial cells by some mechanism induced by injury, cell survival or differentiation in a variety of neuronal cell types such as sensory, ciliary and motor neurons, sympathetic, Ciliary neurotrophic factor (CNTF) is expressed in glial cells within the central and peripheral nervous systems |
| Gene names: |
Ciliary neurotrophic factorCNTF |
| Antibodie's label: |
Biotin |
| Purity: |
Anti-rat CNTF specific antibody was purified by affinity chromatography and then biotinylated |
| Ab raised in: |
Rabbit |
| Type: |
Polyclonal |
| Antigen: |
98%) recombinant rat CNTF (rat CNTF), Produced from sera of rabbits pre-immunized with highly pure (> |
| Immuno application: |
Western Blot, ELISA |
| Antibody advice: |
Sandwich: To detect Rat CNTF by sandwich ELISA (using 100 &, This biotinylated polyclonal antibody, Used in conjunction with compatible secondary reagents, Used in conjunction with compatible secondary reagents the detection limit for recombinant rat CNTF is 1, Western Blot: To detect rat CNTF by Western Blot analysis this antibody can be used at a concentration of 0, allows the detection of at least 0, allows the detection of at least 0, in conjunction with our Polyclonal Anti-Rat CNTF (XP-5114) as a capture antibody, under either reducing or non-reducing conditions, #956, #956, 0 ng/lane, 0 ug/mL of this antibody is required, 1 - 0, 15 - 0, 2 - 0, 2 mg/mL, 2 ng/well of recombinant rat CNTF, 25 - 1, 30 ug/mL, 4 ng/well of recombinant Rat CNTF, 5 - 3, ELISA: To detect rat CNTF by direct ELISA (using 100 &, L/well antibody solution) a concentration of 0, L/well antibody solution) this antibody can be used at a concentration of 0 |
| Keep at: |
Avoid repeated freeze-thaw cycles, Frozen aliquots are stable for at least 6 months when stored at -20 grades C, The reconstituted antibody is stable for at least two weeks at 2-8 grades C, CNTF antibody is stable for at least 2 years from date of receipt at -20 grades C |
| Works with: |
Rat |
| Omim nr: |
116587 |
| Ncbi nr: |
P20294 |
| Vial with antibody: |
Lyophilized |
| NCBI GENE nr: |
25707 |
| GENE symbol: |
Cntf |
| Antigene name: |
ciliary neurotrophic factor |
| Source: |
Rattus norvegicustus norvegicus |
| Protein nr: |
P20294 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
CNTF |
| Short name: |
anti-CNTF Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
antibody to-ciliary neurotrophic factor (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CNTF and IDBG-409278 and ENSG00000242689 and 1270, CNTF and IDBG-637978 and ENSBTAG00000003624 and 100848228, Cntf and IDBG-254935 and ENSMUSG00000079415 and 12803, Extracellular, HCNTF, growth factor activity, this GO :0005127 and ciliary neurotrophic factor receptor binding and molecular function this GO :0005138 and interleukin-6 receptor binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0007165 and signal transduction and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0040007 and growth and biological process this GO :0042517 and positive regulation of tyrosine phosphorylation of Stat3 protein and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0046533 and negative regulation of photoreceptor cell differentiation and biological process this GO :0046668 and regulation of retinal cell programmed cell death and biological process this GO :0048644 and muscle organ morphogenesis and biological process this GO :0048666 and neuron development and biological process this GO :0070120 and ciliary neurotrophic factor-mediated signaling pathway and biological process this GO :0097058 and CRLF-CLCF1 complex and cellular component, this GO :0005127 : ciliary neurotrophic factor receptor binding, this GO :0005127 : ciliary neurotrophic factor receptor binding and also this GO :0005138 : interleukin-6 receptor binding and also this GO :0008083 : growth factor activity, this GO :0005138 : interleukin-6 receptor binding, this GO :0008083 : growth factor activity, ciliary neurotrophic factor |
| Identity: |
2169 |
| Gene: |
CNTF |
More about : CNTF |
| Long gene name: |
ciliary neurotrophic factor |
| Synonyms: |
HCNTF |
| Locus: |
11q12, 1 |
| Discovery year: |
1991-01-07 |
| GenBank acession: |
BC068030 |
| Entrez gene record: |
1270 |
| Pubmed identfication: |
1840538 1714745 |
| RefSeq identity: |
NM_000614 |
| Classification: |
Interleukin 6 cytokine family |
| Havana BLAST/BLAT: |
OTTHUMG00000137476 |
| Locus Specific Databases: |
ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database |