| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
ALEXA FLUOR 594 |
| Host organism: |
Mouse (Mus musculus) |
| Target Protein/Peptide: |
CEA |
| Specificity: |
Highly specific antibody against CEA |
| Modification: |
Not modified |
| Clonality: |
Monoclonal Antibodies |
| Clone: |
5F2 |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from Human CEA/CEACAM5 |
| Gene ID: |
1048 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross Reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
No significant cross reactivity is observed |
| Background information: |
CEACAM 3-CEACAM 8) and 11 pregnancy-specific glyco-protein (PSG 1-PSG 11) members, CEACAM molecules are differentially expressed in epithelial cells or in leucocytes, CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor, It consists of seven CEACAM (CEACAM 1, Over-expression of CEA/ CEACAM 5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker, The CEA family proteins belong to the immunoglobulin (Ig) superfamily and are composed of one Ig variable-like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains, The function of CEACAM family members varies widely: they function as cell adhesion molecules, receptors of Neisseria species and other bacteria, regulators of lymphocyte and dendritic cell activation, tumor suppressors, CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family |
| Purification method: |
Purified by Protein G |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, Aqueous buffered solution containing 100ug/ml BSA, C for 12 months |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CD66e |
| Alternative name 1: |
594 Conjugated, ALEXA FLUOR®, CEA (5F2) Monoclonal Antibody |
| Alternative name 2: |
ALEXA FLUOR 594 Conjugated, CEA (5F2) Monoclonal anti- |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies - small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, specificity and reactivity, Cycles of freezing and thawing should be avoided as such cycles may denature the peptide chains of the antibody and reduce its affinity |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
CEA (5F2) Monoclonal |
| Short name: |
Fluor 594, Anti-CEA (5F2) Monoclonal |
| Technique: |
Monoclonals or monoclonal antibodies |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-CEA (5F2) monoclonal |
| Identity: |
1817 |
| Gene: |
CEACAM5 |
More about : CEACAM5 |
| Long gene name: |
carcinoembryonic antigen related cell adhesion molecule 5 |
| Synonyms gene: |
CEA |
| Synonyms gene name: |
carcinoembryonic antigen-related cell adhesion molecule 5 |
| Locus: |
19q13, 2 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M17303 |
| Entrez gene record: |
1048 |
| RefSeq identity: |
NM_004363 |
| Classification: |
I-set domain containing Immunoglobulin like domain containing CD molecules V-set domain containing Carcinoembryonic antigen related cell adhesion molecule family |
| Havana BLAST/BLAT: |
OTTHUMG00000151061 |