| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
ALEXA FLUOR 594 |
| Host organism: |
Mouse (Mus musculus) |
| Target Protein/Peptide: |
BNP |
| Specificity: |
Highly specific antibody against BNP |
| Modification: |
Not modified |
| Clonality: |
Monoclonal Antibodies |
| Clone: |
H1G3 |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human BNP |
| Gene ID: |
4879 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross Reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
No significant cross reactivity is observed |
| Background information: |
BNP, BNP belongs to a family of structurally similar peptide hormones, BNP is a 32 amino acid peptide with disulfide bond between the cysteine residues Cys10 and Cys26, BNP is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload, C-type natriuretic peptide (CNP) and urodilatin, In earlier studies it has been demonstrated that BNP concentration in blood increases with the severity of congestive heart failure, Quantitative measurement of BNP in blood provides an objective indicator of congestive heart failure severity, These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues, This ring structure shows high homology between different natriuretic peptides (eleven of the 17 amino acid residues are homologous in the ring of each of the natriuretic peptides), vasodilatory and renin inhibitory properties, which includes atrial natriuretic peptide (ANP), Brain natriuretic peptide (BNP) circulates in blood as a peptide hormone with natriuretic |
| Purification method: |
Purified by Protein G |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, Aqueous buffered solution containing 100ug/ml BSA, C for 12 months |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
Brain natriuretic peptide 32, Gamma brain natriuretic peptide, NPPB, NPPB protein, Natriuretic peptide brain type, Natriuretic peptide precursor B, Natriuretic peptides B, BNP 32 |
| Alternative name 1: |
594 Conjugated, ALEXA FLUOR®, BNP(H1G3) Monoclonal Antibody |
| Alternative name 2: |
ALEXA FLUOR 594 Conjugated, BNP(H1G3) Monoclonal anti- |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies - small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, specificity and reactivity, Cycles of freezing and thawing should be avoided as such cycles may denature the peptide chains of the antibody and reduce its affinity |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
BNP(H1G3) Monoclonal |
| Short name: |
Fluor 594, Anti-BNP(H1G3) Monoclonal |
| Technique: |
Monoclonals or monoclonal antibodies |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-BNP(H1G3) monoclonal |