| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
ALEXA FLUOR 594 |
| Host organism: |
Mouse (Mus musculus) |
| Target Protein/Peptide: |
CRPC |
| Specificity: |
Highly specific antibody against CRPC |
| Modification: |
Not modified |
| Clonality: |
Monoclonal Antibodies |
| Clone: |
C11F2 |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
Recombinant CRP protein |
| Gene ID: |
1401 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross Reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
No significant cross reactivity is observed |
| Background information: |
117, 24 kDa), C Reactive Protein mediates activities associated with preimmune nonspecific host resistance, CRP also binds to several nuclear components including chromatin, CRP shows the strongest association with cardiovascular events, It is a pentraxin (cyclic pentameric protein) compound of five identical nonglycosylated subunits of 206 amino acids each (m, It is opsonic, Many clinical studies demonstrated that coronary mortality among patients with unstable angina and elevated CRP is significantly higher comparing with the patients without elevated CRP, Measurements of C reactive protein (hsCRP) in the patients with ischemic heart disease provide a novel method for detecting individuals at high risk of plaque rupture, Studies have revealed that among other markers of inflammation, an initiator of the classical complement cascade and an activator of monocytes/macrophages, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis, that are bound noncovalently to form the physiologic CRP molecule (m, 5 kDa), C Reactive Protein is a major acute phase reactant synthesized primarily in the liver hepatocytes, w, w |
| Purification method: |
Purified by Protein G |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, Aqueous buffered solution containing 100ug/ml BSA, C for 12 months |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
PTX1 |
| Alternative name 1: |
594 Conjugated, ALEXA FLUOR®, CRP (C11F2) Monoclonal Antibody |
| Alternative name 2: |
ALEXA FLUOR 594 Conjugated, CRP (C11F2) Monoclonal anti- |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies - small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, specificity and reactivity, Cycles of freezing and thawing should be avoided as such cycles may denature the peptide chains of the antibody and reduce its affinity |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene: |
CRP |
More about : CRP |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
CRP (C11F2) Monoclonal |
| Short name: |
Fluor 594, Anti-CRP (C11F2) Monoclonal |
| Technique: |
Monoclonals or monoclonal antibodies |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, pentraxin-related (C11F2) monoclonal, antibody to-C-reactive protein |
| Alternative to gene target: |
CRP and IDBG-103911 and ENSG00000132693 and 1401, CRP and IDBG-630749 and ENSBTAG00000013907 and 527553, Crp and IDBG-205690 and ENSMUSG00000037942 and 12944, Extracellular, PTX1, classical pathway and biological process this GO :0007568 and aging and biological process this GO :0008228 and opsonization and biological process this GO :0010288 and response to lead ion and biological process this GO :0010745 and negative regulation of macrophage derived foam cell differentiation and biological process this GO :0010888 and negative regulation of lipid storage and biological process this GO :0015485 and cholesterol binding and molecular function this GO :0030169 and low-density lipoprotein particle binding and molecular function this GO :0030175 and filopodium and cellular component this GO :0030426 and growth cone and cellular component this GO :0033265 and choline binding and molecular function this GO :0042060 and wound healing and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0045087 and innate immune response and biological process this GO :0045471 and response to ethanol and biological process this GO :0050830 and defense response to Gram-positive bacterium and biological process this GO :0051258 and protein polymerization and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071277 and cellular response to calcium ion and biological process this GO :1900006 and positive regulation of dendrite development and biological process, pentraxin-related, protein homodimerization activity, this GO :0001666 and response to hypoxia and biological process this GO :0001849 and complement component C1q binding and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006953 and acute-phase response and biological process this GO :0006954 and inflammatory response and biological process this GO :0006958 and complement activation, this GO :0001849 : complement component C1q binding, this GO :0001849 : complement component C1q binding and also this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding and also this GO :0015485 : cholesterol binding and also this GO :0030169 : low-density lipoprotein particle binding and also this GO :0033265 : choline binding and also this GO :0042803 : protein homodimerization activity, this GO :0005509 : calcium ion binding, this GO :0005515 : protein binding, this GO :0015485 : cholesterol binding, this GO :0030169 : low-density lipoprotein particle binding, this GO :0033265 : choline binding, this GO :0042803 : protein homodimerization activity, C-reactive protein |
| Identity: |
2367 |
| Long gene name: |
C-reactive protein |
| Synonyms gene name: |
C-reactive protein, pentraxin-related |
| Synonyms name: |
pentraxin 1 |
| Locus: |
1q23, 2 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
M11725 |
| Entrez gene record: |
1401 |
| Pubmed identfication: |
3840479 6857266 |
| RefSeq identity: |
NM_000567 |
| Classification: |
Short pentraxins |
| Havana BLAST/BLAT: |
OTTHUMG00000035344 |